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Elsevier

Libros en Toxicología

  • Recent Advances in the Pharmacology of Toxins

    Proceedings of the First International Pharmacological Meeting Stockholm, 22-25 August, 1961
    • 1 Edición
    • H. W. Raudonat
    • Inglés
    Recent Advances in the Pharmacology of Toxins brings together the proceedings of the Second International Pharmacological Meeting of the International Union of Physiological Sciences, held in Prague, Czechoslovakia, on August 20-23, 1963. The meeting provided a forum for discussing advances in the understanding of the pharmacology of toxins and addressed topics ranging from antagonists of bradykinin to the mode of the spread of tetanus toxin in experimental animals. This volume is comprised of 28 chapters and begins with an analysis of the effects of toxins from microorganisms on mammalian cellular metabolism and structure, followed by a review of SRS-A, a slow-reacting substance of anaphylaxis, as a potential factor in the symptoms produced by venoms and toxins. Subsequent chapters explore the release of pharmacologically active lipids by enzymes contained in toxins; the structure and function of some enzymes in snake venoms, with reference to disulfide linkages; biochemistry and pharmacology of small-molecular compounds of cobra venom; and the role of ganglioside in the mode of action of tetanus toxin. This book will be of particular value to pharmacologists and physiologists.

  • Advances in Pharmacological Research and Practice

    Proceedings of the 4th Congress of the Hungarian Pharmacological Society, Budapest, 1985
    • 1 Edición
    • J. Knoll + 1 más
    • Inglés
    Advances in Pharmacological Research and Practice, Volume 1: Pharmacological Protection of the Myocardium presents the proceedings of the 4th Congress of the Hungarian Pharmacological Society, held in Budapest, Hungary in 1985. This book presents a comprehensive view of the development in the fields of pharmacological protection of the myocardium and the pharmacology of the vascular system. Organized into two sections encompassing 70 chapters, this volume begins with an overview of the ischemic biochemical changes with emphasis on the role of cAMP and the protein kinase system. This text then explores the cellular electrophysiological disorders seen in acute myocardial ischemia as well as their pharmacological modification. Other chapters consider the prevention of primary ventricular fibrillation that includes measures aimed at maintaining electrical stability. The final chapter deals with drugs affecting beneficially the pathological lipoprotein levels. This book is a valuable resource for cardiologists and pharmacologists.

  • Bioreduction in the Activation of Drugs

    Proceedings of the Second Biochemical Pharmacology Symposium, Oxford, UK, 25-26 July 1985
    • 1 Edición
    • P. Alexander + 2 más
    • Inglés
    Bioreduction in the Activation of Drugs covers the proceedings of the Second Biochemical Pharmacology Symposium. The book presents papers that cover the applications of bioreduction in drug activation, along with its concerns. The text first presents materials about enzymology, such as overview of enzyme systems involved in bioreduction of drugs and in redox cycling, and reductive role of glutathione in the redox cycling of oxidizable drugs. Next, the book covers papers on bacterial and parasites infection, which include reduction by the gut microflora of animals and human and reduction of nitroimidazoles in vitro and DNA damage. The remaining articles deal with cancer treatment, such as hypoxia-mediated nitro-heterocyclic drugs in the radio- and chemotherapy of cancer, and the biological properties of reduced nitroheterocyclics and possible underlying biochemical mechanisms. The text will be of great use to researchers and practitioners of medicine, pharmacology, and biochemistry.

  • The Physiology and Pharmacology of the Microcirculation

    • 1 Edición
    • Nicholas A. Mortillaro
    • Inglés
    The Physiology and Pharmacology of the Microcirculation, Volume 2, discusses the microcirculatory function of specific organ systems. The first volume of The Physiology and Pharmacology of the Microcirculation presented some general aspects of microcirculatory function and then concentrated on the microcirculation of a specific organ system, namely, brain, eye, heart, and kidneys. This second and final volume continues the presentation of microcirculatory function of specific organ systems. The book begins with a chapter on the microcirculation of the lungs, with a description of its microcirculatory features and current methods of study. This is followed by separate chapters on the microcirculation of the splanchnic organs. These include the stomach, emphasizing hemodynamics, tissue oxygenation, and control of blood flow; the small and large intestine. Subsequent chapters deal with the microcirculatory responses of both the liver and spleen to different physiological and pharmacological challenges; the microcirculation of the skin, with emphasis on human microcirculation; normal and abnormal microcirculatory dynamics in skeletal muscle; microcirculation of bone; and microcirculation of the salivary glands and exocrine pancreas. The final chapter presents a selective review of pathological events involving the microcirculation, with the emphasis directed toward human diseases.

  • Metal Toxicology

    Approaches and Methods
    • 1 Edición
    • Robert A. Goyer
    • Inglés
    Metal Toxicology addresses the effects of metals on human health, as well as their mechanisms of toxicity. Unlike most books on metal toxicity which are organized by individual metals, this book is arranged inan organ-by-organ basis. It deals with unifying mechanisms of metal toxicity within a given tissue, and with exposure of a tissue to more than one metal at a time.

  • Pharmacology for Student and Pupil Nurses and Students in Associated Professions

    • 2 Edición
    • Bernard R. Jones
    • Inglés
    Pharmacology for Student and Pupil Nurses and Students in Associated Professions, Second Edition reviews the progress made in the realm of therapy and the exploration of the drug trends already established. This book explains certain aspects of the International System of Units (SI) as they concern the nursing sphere. Organized into 25 chapters, this edition begins with an overview of the main routes chosen for administering a drug that are influenced by various factors, such as the condition of patient, speed of action, and convenience. This text then examines the various types of laxatives that induce or aid in evacuation of the bowel. Other chapters consider the various drugs and procedures employed in kidney failure. This book discusses as well the types and uses of intravenous infusions. The final chapter deals with the calculations that need to be performed by the nursing staff. This book is a valuable resource for nurses and student nurses.

  • Routes of Drug Administration

    Topics in Pharmacy
    • 1 Edición
    • A. T. Florence + 1 más
    • Inglés
    Routes of Drug Administration covers topics about parenteral and enteral routes of drug administration. The book discusses the anatomy and physiology of administration sites; the formulation and design of delivery systems; and other relevant aspects of biopharmaceutics. The text describes pulmonary delivery, nasal, buccal, and transdermal routes of administration for systemic delivery, as well as a number of systems for more localized therapy with antibiotics. Innovative methods of antibiotic administration, such as continuous and intermittent infusion, endotracheal installation, aerosol delivery, antibiotic-impregnat... catheters, antibiotic-containin... bone cement, and beads, are also considered. Senior undergraduate and postgraduate students in pharmacy, medicine, nursing and allied health sciences and practitioners in these fields, as well as other professionals concerned with the preparation and administration of medicines and the monitoring of drug therapy will find the book useful.

  • Neuropsychopharmacology

    Proceedings of the 7th International Congress of Pharmacology, Paris, 1978
    • 1 Edición
    • C. Dumont
    • Inglés
    Advances in Pharmacology and Therapeutics, Volume 5: Neuropsychopharmacol... contains the proceedings of the 7th International Congress of Pharmacology held in Paris, France, in 1978. The papers explore advances in the understanding of neuropsychopharmacol... and cover topics ranging from anti-schizophrenic drugs to drug pathways in depression treatment. Pharmacological interferences with nonstriatal dopaminergic systems are also discussed. This volume is comprised of 21 chapters and opens by considering the nanomolar affinity of pre- and post-synaptic dopamine receptors for neuroleptics. The next section deals with drug pathways in the treatment of depression, with particular reference to the biochemical mechanisms of depressive states and the therapeutic effects of some antidepressants. The following chapters examine dopamine receptors in the nucleus accumbens; modulation of mesolimbic dopamine mechanisms via serotonin and GABA; how mesocortical dopaminergic neurons react to stress; and the behavioral consequences of the interaction between morphine, substance P, and nonstriatal dopamine neurons. This book will be of interest to practitioners in biosciences, pharmacology, physiology, psychology, neurology, and medicine.

  • Monographs on Fragrance Raw Materials

    A Collection of Monographs Originally Appearing in Food and Cosmetics Toxicology
    • 1 Edición
    • D. L. J. Opdyke
    • Inglés
    Monographs on Fragrance Raw Materials contains a collection of monographs originally appearing in Food and Cosmetics Toxicology from the first issues in 1973 to the last ones in 1978. The monographs are organized in alphabetical order, as a regular feature of Food and Cosmetics Toxicology. This monograph will prove valuable to many readers of Food and Cosmetics Toxicology, as well as to the wider community of scientists and interested consumers.

  • Clinical Pharmacology

    Proceedings of the 7th International Congress of Pharmacology, Paris 1978
    • 1 Edición
    • P. Duchêne-Marullaz + 2 más
    • Inglés
    Clinical Pharmacology provides a detailed discussion on toxicology. This discussion includes the chemotherapy of parasitic diseases. Some parts of the book focus on topics on immunopharmacology. Such topic as the genetic and environmental factors that contribute to individual’s varying response to drugs is explained. The book covers such topics as the methods and models for the isoniazid acetylation polymorphism. The issues that arise in the administration of drugs in the neonatal period are assessed. Another topic of interest is the effects of diseases on the absorption of drugs. The pharmacokinetic and pharmacodynamic characteristics of a drug are evaluated. The pharmacogenetic investigation amobarbital disposition is presented completely. The book then presents the use and consumption of drugs in different locations and some clinical considerations. The procedures and methods of analysis for such drug are also reviewed . The book can serve as a valuable tool for pharmacists, medical doctors, pediatricians, students, and researchers in the field of medicine.

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