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Elsevier

Libros en Toxicología

  • Toxicology Disasters

    Causes and Consequences
    • 1 Edición
    • Sue Ford
    • Inglés
    Toxicology Disasters: Cause and Consequences, a volume in the History of Toxicology and Environmental Health series, provides an historical overview of significant toxicological disasters which involved chemical exposure of humans, animals or the environment. The book documents the timeline of events and the legacy of the resulting exposure which occurred within a specific period of time, but with long lasting consequences. Case studies of toxicological incidents and a wide range of categories, including environmental, industrial, pharmaceutical, domestic and international are not only discussed from a historical perspective but also regarding their impacted toxicology, regulation and our current use of these chemicals.The book will help toxicologists, academics and students from environmental health and toxicology departments, environmental/occupa... health regulators, and industrial hygiene/safety personnel gain a better understanding of the arc of a toxicological disaster from its origins, root causes of the problem, and initial and long-term assessments and management.

  • PFAS Contamination

    Global Prevalence, Toxicological and Ecotoxicological Impacts, and Mitigation Strategies
    • 1 Edición
    • Saranya Narayanasamy + 1 más
    • Inglés
    PFAS Contamination: Global Prevalence, Toxicological and Ecotoxicological Impacts, and Mitigation Strategies offers a comprehensive overview of per- and polyfluoroalkyl substances (PFAS), highlighting their global environmental prevalence, toxicological effects and health risks, and state-of-the-art remediation approaches. This book taps into the increasing recognition of PFAS as “forever chemicals” and explores the widespread contamination of these compounds in water, soil, and air along with their toxicological effects on human health and the ecosystem. It highlights recent advancements in detection methods as well as physicochemical, biological, and emerging remediation technologies, including plasma-based technologies, bioremediation, and advanced nanotechnology-based methods, such as plasma technology, bioremediation, and adsorption methods, with case studies illustrating successful applications. It also examines policy frameworks, regulatory measures, and public health impact of PFAS. PFAS Contamination serves as a vital resource for environmental toxicologists, environmental scientists, environmental consultants, engineers, and regulators studying PFAS prevalence, toxicity mechanisms, remediation, and practical strategies for mitigating PFAS contamination and fostering a deeper understanding of the global efforts to address this critical issue.

  • Micro(nano)plastics in Organ Systems

    Health Impacts, Challenges, and Future Prospects
    • 1 Edición
    • Charan Singh + 4 más
    • Inglés
    Micro(nano)plastics in Organ Systems: Health Impacts, Challenges, and Future Prospects comprehensively discusses the impact of micro(nano)plastics on human health, analyzing their sources, classification, and exposure pathways, while exploring their interactions with biological systems, the potential effects on various organ systems, and concerns related to bioaccumulation and toxicity. The book begins with an in-depth analysis of their classification, sources, and exposure pathways, and progressing through interactions with biological systems and the resulting toxicological effects. The text meticulously examines the implications of these particles on various organ systems—including the gastrointestinal, respiratory, cardiovascular, renal, neurological, reproductive, and metabolic systems—while addressing critical issues such as bioaccumulation, immunological responses, and their potential harmful impact on health. Furthermore, the book delves into recent advances in detection technologies, the development of more sustainable advances such as bioplastic-based nanoparticles, and the pressing need for regulatory frameworks to mitigate the health risks associated with micro(nano)plastics. It is an essential resource for toxicologists, environmental scientists, healthcare professionals, public health advocates, and others interested in the implications of micro(nano)plastics on health.

  • Mitochondrial Intoxication

    • 2 Edición
    • Marcos Roberto de Oliveira
    • Inglés
    Mitochondrial Intoxication, Second Edition offers a comprehensive and fully updated exploration of the impact of toxic molecules on mitochondrial physiology, and the diseases that result from their dysfunction. Divided into three sections, the book opens with a detailed overview of mitochondrial physiology, molecular markers of mitochondrial intoxication and challenges of mitochondrial profiling during pre-clinical studies. It then focuses on endogenous toxicants and their impact on mitochondria, including new chapters on lipids, glucose and microbiota-derived toxicants. Amyloid-β peptide and its impact on mitochondrial dysfunction is also a new addition to this book, as well as inflammation-induced mitochondrial intoxication. The final section explores exogenous toxicants, such as pollutants, food additives, illicit and pharmaceutical drugs, pesticides and heavy metals. The effects of micro- and nanoplastics on mitochondrial function are newly covered. Furthermore, the latest computational tools in mitochondrial toxicity research are investigated. Incorporating the latest advances in the field, “Mitochondrial Intoxication, Second Edition” offers cutting-edge insights on mitochondrial toxicity, and serves as an invaluable resource for researchers and advanced students in cell biology, molecular biology, toxicology, biochemistry, pharmacology, and related fields.

  • Phytotoxicity of Organic Pollutants

    Impacts and Management
    • 1 Edición
    • Golam Jalal Ahammed + 1 más
    • Inglés
    Phytotoxicity of Organic Pollutants: Impacts and Management provides a comprehensive and up‑to‑date overview of how diverse organic pollutants affect plant physiology, growth, and development. Bringing together contributions from leading experts, the book examines the sources, environmental behavior, and biological impacts of major classes of organic pollutants. The volume highlights recent advances in understanding the physiological, biochemical, and molecular mechanisms underlying plant responses to organic pollutant exposure. It also explores plant‑ and microbe‑based remediation strategies, emphasizing their potential to safeguard food quality and ecosystem health. Phytotoxicity of Organic Pollutants: Impacts and Management serves as an interdisciplinary resource for researchers, academics, graduate students, environmental professionals, and industry practitioners working in plant science, ecotoxicology, environmental chemistry, and sustainable remediation.

  • Hazardous Chemicals in Medical Devices

    Safety, Risk Analysis, and Regulations
    • 1 Edición
    • Prakash Srinivasan Timiri Shanmugam + 1 más
    • Inglés
    Hazardous Chemicals in Medical Devices: Safety, Risk Analysis, and Regulations provides a comprehensive overview of the hazardous chemicals used in medical device manufacturing. The book discusses the basics of these chemicals, their presence in various components, and the regulations that govern their use. It also delves into the processes involved in manufacturing and the added chemicals during these stages. With a focus on risk assessment and analysis, the book emphasizes the importance of safety in medical devices and outlines the types of hazards associated with these substances.The book further explains the regulatory classification of hazardous chemicals and the labeling and safety data sheet requirements. It includes a list of notified bodies that discuss hazardous substance data, aiding in risk assessment and toxicological profiling. Additionally, it underscores the critical understanding of toxicological profiles of materials used in medical devices, ensuring that readers are well-informed about the safety measures and regulations in place to protect both manufacturers and users.

  • Comprehensive Toxicology

    • 4 Edición
    • Charlene McQueen
    • Inglés
    Comprehensive Toxicology, Fourth Edition, Fifteen Volume Set continues the legacy that began with the first edition in 1997, serving as an indispensable reference for toxicology researchers. This edition focuses on understanding the mechanisms by which chemicals affect biological systems and cause adverse health effects. Edited by a distinguished editorial board and featuring 400 in-depth contributions from experts around the globe, this comprehensive work spans fifteen volumes and nearly 9,000 pages, covering all major organ systems and general principles of toxicology. This extensively revised edition includes around 30 new chapters on modern testing strategies and novel in vitro models, such as organ-on-a-chip systems.It also explores computational approaches, new risk and safety assessment methods, harmonization, artificial intelligence, and the microbiome. As the most authoritative resource in toxicology, it continues to support researchers, faculty, and students in toxicology, as well as professionals in medical, veterinary, food, environmental, chemical, and pharmaceutical industries and international regulatory agencies.

  • Machine Learning and Artificial Intelligence in Toxicology and Environmental Health

    • 1 Edición
    • Zhoumeng Lin + 1 más
    • Inglés
    Machine Learning and Artificial Intelligence in Toxicology and Environmental Health introduces the fundamental concepts and principles of machine learning and AI, providing clear explanations on applying these methods to toxicology and environmental health. The book delves into predictions of chemical ADMET properties, development of PBPK and QSAR models, toxicogenomic analysis, and the evaluation of high-throughput in vitro assays. It aims to guide readers in adapting machine learning and AI techniques to various research problems within these fields. Additionally, the text explores ecotoxicology assessment, impacts of air pollution, climate change, food safety, and chemical risk assessment.It includes case studies, hands-on computer exercises, and example codes, making it a comprehensive resource for researchers, academics, students, and industry professionals. The book highlights how AI can enhance risk assessment, predict environmental hazards, and speed up the identification of harmful substances.

  • Computational Methods in Medicinal Chemistry, Pharmacology, and Toxicology

    • 1 Edición
    • Muhammad Ishfaq
    • Inglés
    Computational Methods in Medicinal Chemistry, Pharmacology, and Toxicology is a comprehensive resource that offers an advanced overview of computational techniques employed in drug discovery, design, and toxicity prediction. The book discusses various topics, including molecular modeling, virtual screening, machine learning, and network pharmacology. It serves as an essential guide for researchers, practitioners, and students in pharmacology, toxicology, medicinal chemistry, bioinformatics, and systems biology fields, showcasing practical applications and future perspectives on new technologies. In addition to covering computational approaches, the book provides real-world examples of drug discovery, candidate optimization, and safety assessment.Other sections explore computer applications in pharmacology and toxicology and discusses the importance of these methods in advancing medicinal research.

  • Veterinary Toxicology

    Basic and Clinical Principles
    • 4 Edición
    • Ramesh C. Gupta
    • Inglés
    Veterinary Toxicology: Basic and Clinical Principles, Fourth Edition is a unique single reference that provides a comprehensive overview on the basic principles of veterinary toxicology to any student at the DVM, MS, or PhD level while also continuing to serve as a clinical reference for practitioners. The book thoroughly updates toxicologists and advanced students on the newest approaches for diagnosing poisoning cases in all animals from chemicals, plants, and accidental or malicious intents. Many chapters are provided on topics not covered in any previous books, such as target organ toxicity, radiation and radioactive materials, FDA regulatory issues, and ethics in veterinary toxicology.Completel... revised and updated to include the most recent developments in the field animal toxins, toxicokinetics mechanism of action, toxicity, and treatment, this book is an essential resource for researchers, practicing veterinary toxicologists, advanced students in toxicology, poison control centers, as well as environmentalists, marine biologists, and animal scientists.

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