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Libros en Toxicología

The Toxicology of Radioactive Substances
Volume 3.59
1 Edición
A. A. Letavet + 1 más
Inglés
The Toxicology of Radioactive Substances, Volume 3: Iron-59 deals with the experimental results of tests conducted at the Radiotoxicology Laboratory of the Institute of Occupational Hygiene and Disease, Academy of Medical Sciences, U.S.S.R. The book focuses on studies made on iron-59, which is widely used in science and technology, such as in the metal industry and in the research of hemoglobin metabolism in the bone marrow and red cells. Other studies show, however, that there is a long-term detrimental effect of intake of iron-59. The text then gives a brief outline of the physical, chemical, and biological properties of iron. Research also shows that the body's reaction to radioactive substances depends on how these are transmitted to the body and on their physicochemical properties. The effect of prolonged administration of radioactive iron on the electrical activity of the cerebral cortex of animals is analyzed, of which, possibly, the nervous system is most affected. The book notes also the changes in the red blood cells during chronic administration of iron-59 in small doses, wherein the hemoglobin levels increased temporarily. Studies of prolonged exposure to radioactive isotopes during pregnancy of the test animals show that there are significant changes in erythropoiesis, associated with iron deficiency. In another study, the prolonged internal administration of radioactive substances showed phasic changes in the height of electrocardiographic waves of the test animals. The text is suitable for physicists, nuclear scientists, doctors of toxicology, and researchers in nuclear medicine.
Drugs and Youth: The Challenge of Today
1 Edición
Ernest Harms
Inglés
Drugs and Youth: The Challenge of Today mainly focuses on the issue of drug addiction in youth and on how to bring this issue to the knowledge of the concerned sectors. This text first discusses the effects on the fetus and newborn of drug abuse in pregnancy. This book then explains the major drugs adolescents and young adults take, including solvents wherein a survey related to this is also presented in this publication. The effects of these drugs, such as physical and mental illnesses, are also tackled. This text also looks into the approaches in the treatment of adolescent drug addicts, including the withdrawal syndrome, group therapy, and psychotherapy. This book concludes by explaining the religious problematic and aftercare problems with the juvenile drug addict. This publication will be invaluable to medical practitioners, sociologists, social workers, ministers, and students doing a research on drug addiction in youth.
Additional Principles and Methods of Analysis
Analytical Methods for Pesticides, Plant Growth Regulators, and Food Additives, Vol. 5
1 Edición
Gunter Zweig
Inglés
Analytical Methods for Pesticides, Plant Growth Regulators, and Food Additives, Volume V: Additional Principles and Methods of Analysis covers the major advances in the analytical techniques used for the qualitative and quantitative determinations of minute amounts of pesticide and plant growth regulator residues in foods and crops. The book discusses developments in analytical methods (i.e. the polarographic technique, thin-layer chromatography) and their general applications; the analytical aspects of pesticide residue analyses in the environment; and specific analytical methods for formulation and residue analyses of insecticides, fungicides, herbicides and plant growth regulators. Agriculturists, agricultural engineers, toxicologists, and people involved in the study of pesticides and biochemicals will find the book invaluable.
Pharmacology for Student and Pupil Nurses and Student Pharmacy Technicians
1 Edición
Bernard R. Jones
Inglés
Pharmacology for Student and Pupil Nurses and Student Pharmacy Technicians is based on lectures presented to nurses in training for the State Registration and State Enrollment Examinations and to Students in Dispensing. The book presents an account of drugs that are in use or are very likely to be used. The text includes description of drug administration; antacids, gastric sedatives, laxatives, antidiarrheal, and diuretics are discussed in detail. The intravenous infusions, cardiovascular drugs, anti-anemics, hemostatics, and anticoagulants are described as to their effects and functions. A brief anatomy of the human circulatory process is presented. The next types of drugs discussed are those that target the respiratory system — expectorants and cough sedatives. The effects of sedatives, stimulants, analgesics, and anesthesia on the nervous system are discussed in detail. Antibiotics, drugs combating infection, tropical diseases, sera, and vaccines as prophylactic and therapeutic remedies are explained. Other drugs, such as antiseptic and disinfectants, drugs used in endoctrine therapy and malignant diseases, as well as drugs that are locally applied and those used in diagnosis are explained. The process of ordering, storage, and administration of drugs; calculations used in determining safe dosages; and the poisons regulations concerning dangerous and potentially harmful drugs are covered in detail. Pharmacists, student pharmacy technicians, professors of pharmacology, practitioners of general medicines, and specialists with interests in drug therapy will find this reference valuable.
Ions-Cyclic Nucleotides-Cholinergy
Proceedings of the 7th International Congress of Pharmacology, Paris, 1978
1 Edición
J.C. Stoclet
Inglés
Advances in Pharmacology and Therapeutics, Volume 3: Ions – Cyclic Nucleotides – Cholinergy covers the proceedings of the Seventh International Congress of Pharmacology, held in Paris in 1978. This book mainly focuses on studying ions, cyclic nucleotides, and cholinergy. Specifically, this text discusses the pharmacology of calcium homeostasis and presents lectures given in the symposium. The role of cyclic nucleotides in the regulation of muscular tissue functions and the evaluation of cyclic AMP and cyclic GMP are also looked into. This text presents in its latter part papers on chemical structure and cholinergic activity. This volume will be valuable to students and experts in the field of pharmacology, therapeutics, and related fields.
Ingredient X
The Production of Effective Drugs
1 Edición
Louis C. Schroeter
Inglés
Ingredient X: The Production of Effective Drugs deals with various aspects of pharmaceutical research and development, with emphasis on the importance of formulation ingredients on drug effectiveness and the role of the pharmaceutical development scientist in designing dosage forms for modern drugs. More than 50 illustrations are used to explain experiments and ""tools of the trade"". This book is comprised of four chapters and opens with an overview of research and development in the pharmaceutical industry, paying particular attention to the kind of work done by scientists according to the degree or level of training. The additives or so-called ""inert"" ingredients used in drug formulation are also considered. The next chapter explains how adding just the right amount of some ""inert"" ingredient—a factor X—can enhance the acceptability of a product to the user. The importance of maintaining drug potency in a dosage form, mainly through refrigeration or storage in cool places, is then discussed. The final chapter looks at the factors to consider to achieve the best possible drug formulation and most effective dosage form, including the safety factor. The need to establish correlations between laboratory quality tests and product performance during the development phase is highlighted. This monograph will be a useful resource for pharmacologists and pharmaceutical development scientists.
Acute Drug Abuse Emergencies
A Treatment Manual
1 Edición
Peter G. Bourne
Inglés
Acute Drug Abuse Emergencies: A Treatment Manual presents the most commonly encountered drug abuse emergencies. This book discusses how various drug-related conditions should be managed by practicing physicians and all those who are dealing with drug abusers. Organized into nine parts encompassing 28 chapters, this book begins with an overview of the various emergency drug reactions, including behavioral disturbances, organ malfunction, central nervous system depression, exacerbation of pre-existing illness, or combinations. This text then examines the profile of a typical heroin overdose victim. Other chapters consider severe poisoning due to nonbarbiturate sedative overdosage. This book discusses as well the types of adverse reactions to marihuana and the dangers of marihuana use. The final chapter deals with the ease of synthesis and the potency of arylcyclohexylamines as a mind-altering drug. This book is a valuable resource for toxicologists, emergency room physicians, and nurses. Readers who are dealing with drug abusers will also find this book extremely useful.
Evaluation of Drug Activities
Pharmacometrics
1 Edición
D R Laurence + 1 más
Inglés
Evaluation of Drug Activities: Pharmacometrics, Volume 1 provides a review and critical discussion of general and special pharmacological methods used in the search of new drugs. This book discusses the fundamental difference between a pharmacological study and a bio-assay in the nature of the biological activity. Organized into two parts encompassing 19 chapters, this book begins with an overview of the pharmacological and toxicological studies on animals. This text then discusses the method of producing clinically successful drugs. Other chapters consider the objective of toxicity testing in determining the complications arising from the pharmacological action of the drug and also in discovering any unexpected side-effects. This book discusses as well the pharmacological effects and heredity in laboratory animals. The final chapter deals with the various aspects of hypertensive disease and its treatment. This book is a valuable resource for scientists, biologists, physiologists, pharmacologists, biochemists, physicians, clinicians, and research workers.
Drug Testing
1 Edición
John Fay
Inglés
Drug Testing focuses on the contributions of drug testing in the identification of the state of drug abuse and the implementation of policies and regulations making drug use unacceptable either socially or in the workplace. The book first gives an overview of drug-testing policy, facilitating drug testing and treatment, challenges to drug-testing programs, and state, local, and federal legislation on drug testing. The text then defines the problem of drug abuse, including dimensions of abuse, defining the problem and the needs of employers, employing a drug abuse survey, and treatment modalities. The manuscript ponders on the development of a drug-testing policy, education of employees, and training of supervisors. Discussions focus on the nature of learning, principles of supervision, training process, program implementation, basic assumptions, final policy content, and problematic issues. The implementation of a drug-testing program, collection of specimens for drug testing, and understanding the drug testing program are also underscored. The publication is a valuable reference for readers interested in drug testing policies, treatment, and effects of drug abuse in the workplace.
Marijuana
Effects on Human Behavior
1 Edición
Loren L. Miller
Inglés
Marijuana: Effects on Human Behavior attempts to synthesize much of the existing experimentation concerning the acute and chronic effects of marijuana and its derivatives on human behavior. The book opens with a chapter on the strategies for conducting research on marijuana. It also describes a clinical study at the University of British Columbia. The next chapter discusses the issues that have beclouded the question of legalization of marijuana in the United States. This is followed by separate chapters on the effects of marijuana on motor and mental performance; marijuana-memory research; a model of attention which can be used to describe the effects of marijuana use on cognition; and the effects of marijuana on neuropsychological functioning and learning. Subsequent chapters examine the behavioral actions of cannabis in man; compare the behavioral actions of cannabinoids in humans with those found in infrahumans, with special reference to acquisition and retention processes, timing behavior, state-dependent learning, and attention; and investigate the long-term effects of cannabis use.