Saltar al contenido principal
Elsevier

Libros en Ciencias de la Vida

  • Mechanisms of Cytotoxicity by NK Cells

    • 1 Edición
    • Ronald Herberman
    • Inglés
    Mechanisms of Cytotoxicity by NK Cells is the resulting book of a workshop focused on the studies that enhance understanding of the basic mechanisms involved in the function and regulation of NK cells. The book presents the status of knowledge of the mechanisms responsible for the cytotoxic effects of NK cells and the regulation of their activity. The text is further divided into five major sections according to the sequence of the workshop sessions. A separate chapter from the sections has been included at the beginning of the book. The introductory chapter clarifies some points in the subject area of NK cells, particularly its definition. The heterogeneity of NK cells is also discussed in this chapter. Then, the book presents the major topics, including the purification and characterization of NK cells and NK target structures and recognition sites. The mechanisms of postrecognition interactions between NK cells and targets; regulation of NK activity and NK cells; and cultured cells with NK-like activity are also discussed. This book will serve as a helpful guide to students and professionals (scientists, researchers, and professors) in the fields of immunology, biology, microbiology, biochemistry, among others.

  • Pyrethrum

    The Natural Insecticide
    • 1 Edición
    • John Casida
    • Inglés
    Pyrethrum: the Natural Insecticide covers the papers presented at the 1972 ""International Symposium on Recent Advances with Pyrethrum the Natural Insecticide"" held in conjunction with the American Institute of Biological Sciences Silver Anniversary Meeting at the University of Minnesota, Minneapolis. It deals with all aspects of pyrethrum, including its history, production, chemistry, biochemistry, toxicology, pharmacology, and agricultural applications. The introductory part addresses the early history of pyrethrum, its recognition as a modern insecticide, and its worldwide production. The chemistry and biochemistry parts discuss the composition, isolation, structure, synthesis, biosynthesis, metabolism, and action on enzyme systems of natural pyrethrins extracted from pyrethrum flower. The book also examines the toxicology of pyrethrum and its constituents to mammals, fish, and wildlife, as well as tests for possible teratogenic, carcinogenic, mutagenic, and allergenic activities. Finally, it discusses the domestic and agricultural applications of pyrethrum. Considering its desirable features, researchers find pyrethrum unsurpassed by any type of synthetic organic insecticide and even by the best synthetic analogs or pyrethroids.

  • Pertussis Toxin

    • 1 Edición
    • Ronald Sekura
    • Inglés
    Pertussis Toxin presents the proceeding of the Pertussis Toxin Conference, held in Bethesda, Maryland, on September 20–21, 1984. This book discusses the perspective of the pertussis toxin and the potential role of the toxin in the development of new acellular pertussis vaccines. Organized into 13 chapters, this text begins with an overview of the biological activities of pertussis vaccine, which enhanced the production of antibodies to antigens. This book then examines the interesting action of pertussis vaccine to stimulate antibody production, particularly as an effective adjuvant for the production of IgE isotype of antibodies. Other chapters consider the experimental approaches used in the study of the mechanisms by which hormones produce their physiological effect. The final chapter examines the several features of the Bordetella adenylate cyclase toxin, which suggest that the molecule may follow the A/B model proposed for a number of bacterial toxins. This book is a valuable resource for toxicologists, immunologists, bacteriologists, and pharmacologists.

  • Nuclear Trafficking

    • 1 Edición
    • Carl Feldherr
    • Inglés
    Nuclear Trafficking is a summary of the state of knowledge in nuclear trafficking, and is organized into five parts. The book begins by discussing the diffusion and signal-mediated transport through the pores. It then looks into the detailed accounts of pore structure and composition, nuclear localization signals, signal binding proteins, RNA efflux, and biochemical factors influencing nucleocytoplasmic exchange. This book will be very useful to those people new to this field of interest.

  • Current Topics in Bioenergetics

    • 1 Edición
    • C.P. Lee
    • Inglés
    Current Topics in Bioenergetics, Volume 16 focuses on photosynthetic electron transfer, ATP-synthesizing reactions, and nitrogen fixation. It looks at the application of biochemistry and biophysics in the exploitation of gene isolation, sequencing, and analysis of structure and function. It also reviews photosystems I and II and electron transfer reactions in eukaryotic chloroplasts of more modern plants as well as in photosynthetic membranes of the very ancient cyanobacteria. Organized into seven chapters, this volume begins with an overview of photosystems I and II. Then, it discusses the ATP synthesis in chloroplasts, with special attention given to the genes and their protein products that produce the ATP synthase complexes of the plant mitochondria and chloroplasts. The reader is then introduced to the mechanism of proton gradient formation and calcium-gated control of the type of gradient formed, the evidence for localized domains of proton accumulation, the reaction center of purple bacteria, and the physical aspects of electron transfer. The final chapter examines the nitrogen fixation in plants and bacteria, with emphasis on the metabolic origins of the reducing power and ATP used in nitrogen fixation. Biophysicists, biochemists, and others interested in bioenergetics will find this book highly informative.

  • Development and Evolution of Brain Size

    Behavioral Implications
    • 1 Edición
    • Martine Hahn
    • Inglés
    Development and Evolution of Brain Size: Behavioral Implications contains the proceedings of a symposium entitled ""Development and Evolution of Brain Size: Behavioral Implications,"" held at William Paterson College in Wayne, New Jersey, in April 1978. The papers explore the relationship between evolution and development and its implications for brain size and behavior. This book is comprised of 18 chapters and begins with an overview of the brain-behavior relationship, with emphasis on the importance of brain size for behavior; the effects of genetic selection for brain size on brain substructures and behavior; and whether genetic and environmental manipulations of brain size have similar consequences. The next two chapters explain evolutionary theory and the evolution of the human brain as well as diversity in brain size. A general model for brain evolution that offers some synthetic possibilities for approaching the questions of brain evolution, size, allometry, and reorganization is then described. The correlation between cerebral indices and behavioral differences is also discussed, along with biochemical correlates of selective breeding for brain size. The results of an experiment that assessed the effects of early undernutrition on brain and behavior of developing mice are presented. This monograph should be of interest to students and practitioners in a wide range of disciplines, including evolutionary biology and clinical psychology.

  • Methods in Mycoplasmology V2

    Diagnostic Mycoplasmology
    • 1 Edición
    • Joseph Tully
    • Inglés
    Methods in Mycoplasmology, Volume II: Diagnostic Mycoplasmology is the second of a two-volume series that resulted from cumulative efforts to meet the need for standardized techniques in mycoplasmology. The book is organized into five sections. Section A discusses techniques for isolating mycoplasmas from humans. These include the recovery of mycoplasmas from the respiratory and genitourinary tracts, from blood and special tissues, and serological Identification of mycoplasmas from humans. Section B focuses on techniques for isolating mycoplasmas from animals, including the recovery and identification of avian, bovine, caprine, ovine, canine, and feline mycoplasmas. Section C presents techniques for isolating mycoplasmas from cell cultures. These include agar and broth techniques, the use of indicator cell lines, and DNA fluorochrome staining. Section D discusses techniques for isolating mycoplasmas from plants and insects. Section E describes some of the techniques that are useful in evaluating the pathogenicity of mycoplasmas, ureaplasmas, and spiroplasmas. Section F defines some of the techniques useful in virus detection by electron microscopy and presents methods for isolating and characterizing viruses from both mycoplasmas and spiroplasmas.

  • Isoenzymes In Biology and Medicine

    • 1 Edición
    • Albert Latner
    • Inglés
    Isoenzymes in Biology and Medicine attempts to give an account of the study of isoenzymes in relation to humans, animals, insects, higher plants, fungi, protozoa, algae, and bacteria. This book discusses the chemical structure, physiological aspects, metabolic role, and function of isoenzyme observations in genetic, ontogenic, and phylogenic studies. A detailed account of the use of isoenzyme in the diagnosis and pathogenesis of disease and control of therapy is also provided. This text likewise considers the isoenzymes of the oxidoreductases, transferases, and hydrolases, including its relation to clinical medicine. This publication is intended for biochemists, biologists, clinical biochemists and physicians.

  • Dimensions In Health Research: Search For The Medicines Of Tomorrow

    • 1 Edición
    • Herbert Weissbach
    • Inglés
    Dimensions in Health Research: Search for the Medicines of Tomorrow is a collection of papers presented at the 1977 Symposium on Dimensions in Health Research: Search for the Medicines of Tomorrow, held in Basel, Switzerland, sponsored by the Roche Research Foundation for Scientific Exchange and Biomedical Collaboration. This symposium is organized in honor to Professor Alfred Pletscher, a known neurobiologist who led the discovery of drugs for the treatment of various central nervous disorders. This book is organized into three section encompassing 28 chapters. The first section covers the molecular biological aspects of gene expression; the biosynthesis of human interferon; the concept of DNA damage and repair; and the link between advances in molecular genetics and medicine. The second section discusses the pertinent advances in understanding the mechanism of immune system and its components. The third section surveys the trends in pharmacotherapy based on monoaminergic, adenosine triphosphate, gamma-amino butyric acid, amino acid, and peptide mechanisms. This book will prove useful to researchers in the fields of molecular biology, immunology, and neurobiology.

  • Plant Disease: An Advanced Treatise

    How Plants Defend Themselves
    • 1 Edición
    • James G. Horsfall
    • Inglés
    Plant Disease An Advanced Treatise, Volume V: How Plants Defend Themselves describes the active, passive, physical, chemical, mechanical, and physiological defense systems of plants against the pathogens. Divided into 23 chapters, this volume discusses theories, experimental approaches, and ways to help plant defend themselves. The opening chapters of this volume deal with certain general aspects of plant defense, such as the theories of “tolerance to disease” and “the time sequence of defense”, including a dynamic model of defense. A chapter discusses how plant populations defend themselves in natural ecosystem and the implications of disease management on agroecosystems. Considerable chapters examine the defense by the host by analogy with defense of a medieval castle, such as perimeter, internal, and chemical defenses. Discussions on the defenses triggered by the invading pathogen; recognition and compatibility phenomena; the concept of hypersensitivity; the role of phytoalexins in defense; and the metabolic detoxification done by plants to suffer less damage from toxins are provided. This volume also discusses the theory and mechanisms of hypovirulence and hyperparasitism. The concluding chapters summarize the effects of numerous nutrients on disease and the mechanisms involved. This volume is an invaluable source for plant pathologists, mycologists, advanced researches, and graduate students.

Temas relacionados