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Elsevier

Libros en Farmacología

  • Pharmacognosy

    Fundamentals, Applications and Strategies
    • 1 Edición
    • Rupika Delgoda
    • Simone Badal McCreath
    • Inglés
    Pharmacognosy: Fundamentals, Applications and Strategies explores a basic understanding of the anatomy and physiology of plants and animals, their constituents and metabolites. This book also provides an in-depth look at natural sources from which medicines are derived, their pharmacological and chemical properties, safety aspects, and how they interact with humans. The book is vital for future research planning, helping readers understand the makeup, function, and metabolites of plants in a way where the history of their usage can be linked to current drug development research, including in vitro, in vivo, and clinical research data. By focusing on basic principles, current research, and global trends, this book provides a critical resource for students and researchers in the areas of pharmacognosy, pharmacy, botany, medicine, biotechnology, biochemistry, and chemistry.

  • Individualized Drug Therapy for Patients

    Basic Foundations, Relevant Software and Clinical Applications
    • 1 Edición
    • Roger W Jelliffe + 1 más
    • Inglés
    Individualized Drug Therapy for Patients: Basic Foundations, Relevant Software and Clinical Applications focuses on quantitative approaches that maximize the precision with which dosage regimens of potentially toxic drugs can hit a desired therapeutic goal. This book highlights the best methods that enable individualized drug therapy and provides specific examples on how to incorporate these approaches using software that has been developed for this purpose. The book discusses where individualized therapy is currently and offers insights to the future. Edited by Roger Jelliffe, MD and Michael Neely, MD, renowned authorities in individualized drug therapy, and with chapters written by international experts, this book provides clinical pharmacologists, pharmacists, and physicians with a valuable and practical resource that takes drug therapy away from a memorized ritual to a thoughtful quantitative process aimed at optimizing therapy for each individual patient.

  • Developing Solid Oral Dosage Forms

    Pharmaceutical Theory and Practice
    • 2 Edición
    • Yihong Qiu + 4 más
    • Inglés
    Developing Solid Oral Dosage Forms: Pharmaceutical Theory and Practice, Second Edition illustrates how to develop high-quality, safe, and effective pharmaceutical products by discussing the latest techniques, tools, and scientific advances in preformulation investigation, formulation, process design, characterization, scale-up, and production operations. This book covers the essential principles of physical pharmacy, biopharmaceutics, and industrial pharmacy, and their application to the research and development process of oral dosage forms. Chapters have been added, combined, deleted, and completely revised as necessary to produce a comprehensive, well-organized, valuable reference for industry professionals and academics engaged in all aspects of the development process. New and important topics include spray drying, amorphous solid dispersion using hot-melt extrusion, modeling and simulation, bioequivalence of complex modified-released dosage forms, biowaivers, and much more.

  • Side Effects of Drugs Annual

    A Worldwide Yearly Survey of New Data in Adverse Drug Reactions
    • 1 Edición
    • Volumen 38
    • Inglés
    Side Effects of Drugs Annual: A Worldwide Yearly Survey of New Data in Adverse Drug Reactions was first published in 1977, and has been continually published as a yearly update to the voluminous encyclopedia Meyler's Side Effects of Drugs. Each annual provides clinicians and medical investigators with a reliable and critical survey of new data and trends in the area of adverse drug reactions and interactions, with an international team of specialists contributing their expertise each year.

  • Cardioskeletal Myopathies in Children and Young Adults

    • 1 Edición
    • John Lynn Jefferies + 3 más
    • Inglés
    Cardioskeletal Myopathies in Children and Young Adults focuses on plaques that kill people in their 40’s-50’s and the way they start to form in young adulthood. The Annals of Family Medicine report that approximately half of young adults have at least one cardiovascular disease risk factor (Mar 2010), and an increase in cardiovascular mortality rates in young adults was substantiated in a study at Northwestern Medicine (Nov 2011). Given the increasing recognition of genetic triggers behind all types of cardiovascular disease, and the growing population of young adults with primary or acquired myocardial disease, the need has arisen for a reference that offers a comprehensive approach to the understanding of basic, translational, and clinical aspects of specific muscle diseases while making the link between young adult and adult health.

  • Pharmacology in Drug Discovery and Development

    Understanding Drug Response
    • 2 Edición
    • Terry P. Kenakin
    • Inglés
    Pharmacology in Drug Discovery and Development: Understanding Drug Response, Second Edition, is an introductory resource illustrating how pharmacology can be used to furnish the tools necessary to analyze different drug behavior and trace this behavior to its root cause or molecular mechanism of action. The concepts discussed in this book allow for the application of more predictive pharmacological procedures aimed at increasing therapeutic efficacy that will lead to more successful drug development. Chapters logically build upon one another to show how to characterize the pharmacology of any given molecule and allow for more informed predictions of drug effects in all biological systems. New chapters are dedicated to the interdisciplinary drug discovery environment in both industry and academia, and special techniques involved in new drug screening and lead optimization. This edition has been fully revised to address the latest advances and research related to real time kinetic assays, pluridimensional efficacy, signaling bias, irreversible and chemical antagonism, allosterically-induc... bias, pharmacokinetics and safety, target and pathway validation, and much more. With numerous valuable chapter summaries, detailed references, practical examples and case studies throughout, Dr. Kenakin successfully navigates a highly complex subject, making it accessible for students, professors, and new researchers working in pharmacology and drug discovery.

  • Anticandidal Agents

    • 1 Edición
    • Awanish Kumar
    • Inglés
    Anticandidal Agents provides the latest information on candida drug resistance and its remedial implications. In this compilation, users will find a comprehensive view on overcoming resistance in anticandidal drugs, along with information on novel molecules. Candida albicans is an opportunistic pathogenic fungus responsible for life threating invasive and nosocomial infections across the globe. Candidiasis is a major cause of morbidity among immunocompromised patients. Infections caused by non-albicans candida like C. glabrata, C. parapsilosis, and C. tropicalis have also imposed a serious threat in the last few decades. Current treatment of candidiasis relies primarily on antifungal agents broadly categorized as azoles, polyenes, echinocandins, allylamines, and pyrimidines. Lately, antifungal resistance has emerged to be an obstruction of current treatment regime. A number of reasons are described in detail. Understanding the mechanisms of resistance is crucial for developing strategies for overcoming the hindrance in current therapeutics.

  • Life-Threatening Effects of Antipsychotic Drugs

    • 1 Edición
    • Peter Manu + 2 más
    • Inglés
    Life-Threatening Effects of Antipsychotic Drugs describes in detail more than 20 life-threatening effects associated with antipsychotics, presents the best available data on their incidence and case fatality, and gives comprehensive advice on diagnosis, management and preventive strategies. In addition, the book discusses the benefit of antipsychotic medication in a range of therapeutic indications, and demonstrates the gain in life-expectancy associated with clozapine use in severe mental illness despite its serious, potentially life-threatening adverse effects.

  • Regenerative Medicine for Peripheral Artery Disease

    • 1 Edición
    • Emile R Mohler + 1 más
    • Inglés
    Regenerative Medicine for Peripheral Artery Disease is a comprehensive and up-to-date resource on the use of regenerative medicine for the treatment of peripheral arterial disease. This reference includes a general overview of regenerative medicine and covers important vascular topics, including intermittent claudication and critical limb ischemia, with important mechanisms clearly presented in full color images throughout the book. This important reference includes clear and concise information on both human clinical trials, as well as important and pertinent animal studies, and is a must-have reference for researchers and practitioners of peripheral artery disease.

  • Pyrantel Parasiticide Therapy in Humans and Domestic Animals

    • 1 Edición
    • Alan A. Marchiondo
    • Inglés
    Pyrantel Parasiticide Therapy in Humans and Domestic Animals presents a single source history and reference on the parasiticide activity and pharmacology of the tetrahydropyrimidine... and their salts in humans and domestic animals, also collating evidence that resistance to pyrantel has developed in human and domestic animal nematodes. Other books of this nature have been compiled historically for specific anthelmintic compounds, but none has been written to date for the pyrantel family of drugs. Pyrantel, a nicotinic receptor agonist, has been used in domestic animal and human medicine since the 1970’s to control two important nematode groups, the hookworms and the roundworms. Given the zoonotic potential of these parasites, pyrantel has served a dual role in helping to protect the health of both domestic animals and the public for more than 45 years.

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