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Elsevier

Libros en Farmacología

  • Biochemistry of Drug Metabolizing Enzymes

    Trends and Challenges
    • 1 Edición
    • Muhammad Sajid Hamid Akash + 1 más
    • Inglés
    Biochemistry of Drug Metabolizing Enzymes: Trends and Challenges is a complete and well-integrated reference on their mechanisms of action, their role in diseases, agents responsible for their deactivation, and their malfunction. Chapters explain the biochemistry of DMEs, including biochemical activation, functions, computational approaches, different contaminants on the action and function of DMEs, and describe the importance of DMEs in the drug development process. Conditions covered include metabolic diseases, cardiovascular diseases, neurological diseases, physiological diseases, xenobiotics and inflammatory responses, and their contribution in the malfunctioning of drug metabolizing enzymes. This book is the perfect resource for pharmacology and biochemistry researchers to understand the principles of DMEs. Researchers in the corporate environment will also benefit from the comprehensive list of diseases associated with malfunction of DMEs.

  • Brenner and Stevens’ Pharmacology

    • 6 Edición
    • Craig W. Stevens
    • Inglés
    More detailed than an outlined review but less overwhelming than an encyclopedic reference, Brenner and Stevens’ Pharmacology, 6th Edition, focuses on the essential principles you need to know in a concise, easy-to-understand manner. Authored by Craig W. Stevens, PhD, this highly illustrated introductory text helps you learn and retain key information in pharmacology—taking you from course exams and the USMLE Step 1 right through to clinical practice. New and extensively revised content keeps you up to date with the latest pharmacologic mechanisms and applications.

  • Herbal Bioactive-Based Drug Delivery Systems

    Challenges and Opportunities
    • 1 Edición
    • Inderbir Singh Bakshi + 3 más
    • Inglés
    Herbal Bioactive-Based Drug Delivery Systems: Challenges and Opportunities provides a wide-ranging, in-depth resource for herbal bioactives, including detailed discussion of standardization and regulations. The book first explores specific drug delivery systems such as gastrointestinal, ocular, pulmonary, transdermal, and vaginal and rectal. It then discusses novel applications for nano, cosmetics, nutraceuticals, wound healing and cancer treatment. Finally, there is a section focusing on standardization and regulation which includes an enhancement of properties. This book is an essential resource for pharmacologists, pharmaceutical scientists, material scientists, botanists, and all those interested in natural products and drug delivery systems developments.

  • Behavioral Pharmacology of Drug Abuse: Current Status

    • 1 Edición
    • Volumen 93
    • Inglés
    Behavioral Pharmacology of Drug Abuse: Current Status, Volume 93 provides an update on our current understanding of animal and human behavioral pharmacology in major classes of drugs of abuse, including nicotine, alcohol, opioids, psychostimulants, and hallucinogens, drug-environment interactions, neurochemical mechanisms and medications developments. This volume updates the field of behavioral pharmacology based on new knowledge gained in the past decade.

  • Allosteric Modulation of G Protein-Coupled Receptors

    • 1 Edición
    • Robert Laprairie
    • Inglés
    Allosteric Modulation of G Protein-Coupled Receptors reviews fundamental information on G protein-coupled receptors (GPCRs) and allosteric modulation, presenting original research in the area and collectively providing a comprehensive description of key issues in GPCR allosteric modulation. The book provides background on core concepts of molecular pharmacology while also introducing the most important advances and studies in the area. It also discusses key methodologies. This is an essential book for researchers and advanced students engaged in pharmacology, toxicology and pharmaceutical sciences training and research. Many of the GPCR-targeted drugs released in the past decade have specifically worked via allosteric mechanisms. Unlike direct orthosteric-acting compounds that occupy a similar receptor site to that of endogenous ligands, allosteric modulators alter GPCR-dependent signaling at a site apart from the endogenous ligand. Recent methodological and analytical advances have greatly improved our ability to understand the signaling mechanisms of GPCRs. We now know that allostery is a common regulatory mechanism for all GPCRs and not – as we once believed – unique to a few receptor subfamilies.

  • The Pharmacological Potential of Cyanobacteria

    • 1 Edición
    • Graciliana Lopes + 2 más
    • Inglés
    The Pharmacological Potential of Cyanobacteria explores the bioactive compounds isolated from cyanobacteria and their relationship to human health and biotechnological applications. The book presents an overview of the chemistry and ecology of cyanobacteria, focusing on culture needs and techniques of biomass production. It is organized according to the different biological activities and biotechnological applications of compounds discovered in recent years. Besides biological activity, the mechanism of action of compounds is explained, along with molecular structure. Finally, compounds already used in therapeutics and biotechnology, as well as those in phases of approval or clinical trials are explored. Each chapter is written by a different research group with expertise in the field and publications in peer reviewed journals. Researchers and students in pharmaceutical academic research, pharmaceutical industrial sector personnel, health professionals, and nutritionists will find this book to be very useful.

  • Tamoxifen Tales

    Suggestions for Scientific Survival
    • 1 Edición
    • V. Craig Jordan
    • Inglés
    Tamoxifen Tales: Suggestions for Scientific Survival presents a case study describing the academic journey of teams behind major advances in medical sciences, highlighting lessons learned that are applicable to the next generation of scientists. This book provides a manual on the successful mentoring of young scientists, including stories describing how training experience shaped careers to become leaders in academia and the pharmaceutical industry. The book documents Professor V. Craig Jordan’s 50-year career in medical sciences that led to the discovery and development of Selective Estrogen Receptor Modulators (SERMs), which became the standard of women’s healthcare around the world. Additionally, it illustrates the versatility of a scientist with a commitment to serving societies. This important resource will be a useful and interesting book for established medical scientists, research mentors and advanced students wanting to chart a successful and impactful research career.

  • Stimuli-Responsive Nanocarriers

    Recent Advances in Tailor-Made Therapeutics
    • 1 Edición
    • Virendra Gajbhiye + 2 más
    • Inglés
    Stimuli-Responsive Nanocarriers: Recent Advances in Tailor-Made Therapeutics compiles dispersed knowledge into a complete and comprehensive source to help researchers understand and progress stimuli-responsive nanocarriers. The book contains recent advancements made in the field of stimuli-responsive nanocarriers with their application in controlled drug delivery against various diseases. It focuses on the design, mechanism, construction, therapeutic application and future challenges of stimuli-responsive nanocarriers which will help new researchers in designing next generation tailor-made advanced therapeutics. Finally, the book covers future aspects and challenges present in the route of development of stimuli responsive nanocarriers for disease therapeutics. Various recent advances and biomedical applications assembled in this book will guide scientists on how to design and develop novel controlled drug release systems.

  • Medical Pharmacology and Therapeutics

    • 6 Edición
    • Derek G. Waller + 1 más
    • Inglés
    Medical Pharmacology & Therapeutics provides all the information medical and healthcare students need throughout their degree programme and beyond, including for professional qualifications such as the PSA.This all-round textbook covers basic pharmacology through to drug prescribing in clinical contexts, covering the pathogenic mechanisms of disease; drug actions, side effects, and the therapeutic principles of drug use. It takes a helpful systems-based approach that orders information according to body systems and disease areas, rather than by drug class.Now in its sixth edition, the book has been fully updated to include latest scientific understanding of drug action and administration and current best practice in prescribing medications, informed by the latest national guidelines.

  • Atkinson's Principles of Clinical Pharmacology

    • 4 Edición
    • Shiew-Mei Huang + 3 más
    • Inglés
    **Selected for Doody’s Core Titles® 2024 in Pharmacology**Atkins... Principles of Clinical Pharmacology, Fourth Edition is the essential reference on the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This well-regarded survey continues to focus on the basics of clinical pharmacology for the development, evaluation and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the fourth edition has been thoroughly updated to provide readers with an ideal reference on the wide range of important topics impacting clinical pharmacology.

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