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Elsevier

Libros en Ciencias de la Vida

  • Gender Affirming Hormone Therapy in Humans

    Evidence from Murine Models
    • 1 Edición
    • Jeffrey David Zajac
    • Inglés
    Gender Affirming Hormone Therapy in Humans: Evidence from Murine Models is an unprecedented reference for scientists, researchers, students and anyone interested in this field of research. The book is a review of the current state of mouse animal models of relevance to transgender health. It's divided into chapters specific for different tissues in which mouse models are described and their relevance to human health is discussed. This is a novel reference summarizing what these models demonstrate about the benefits and risks of GAHT and the most effective and lowest risk approach to treatment. The models suggest applications of this research to human studies and treatment of transgender people. There is an expanding number of transgender people with are few evidence based books that address this field relating to the importance and growing role of murine models.

  • Molecular Pathology

    The Molecular Basis of Human Disease
    • 3 Edición
    • Gregory J. Tsongalis + 1 más
    • Inglés
    Molecular Pathology: The Molecular Basis of Human Disease, Third Edition is a comprehensive reference that explores the molecular mechanisms and basis of major human diseases. Expertly crafted, this book is designed for use as a teaching tool for medical students, biomedical graduate students, and allied health students. It serves as an advanced resource for pathology residents, postdoctoral fellows, basic scientists, and physician scientists engaged in disease-related research, presenting traditional pathology in the context of translational molecular medicine. In this new edition, the chapters have been fully updated and rearranged for better logical flow.Notably, four new chapters have been included, covering topics such as the pathogenesis of fibrotic diseases, mechanisms of mutation, molecular basis of soft tissue disease and pathology, and pathogenesis and pathophysiology. The book remains an invaluable reference for anyone seeking a deeper understanding of the molecular aspects of human disease.

  • Empowering Health through Lifestyle Medicine

    The Essential Guide for Preventing and Managing Chronic Disease
    • 1 Edición
    • John Anthony Stevens
    • Inglés
    Empowering Health through Lifestyle Medicine: The Essential Guide for Preventing and Managing Chronic Disease is an evidenced-based health discipline for use by anyone in the healthcare profession including clinicians and public health and for those researching illness prevention and chronic disease management to improve health research practice and patient outcomes. Combining the best available research with personal insights and experience and using the Lifestyle Medicine 6 pillar framework, the book engages readers not only in the description and efficacy of LM but also in the knowledge, concepts and behaviors to better prevent and manage nutrition, physical activity, stress, mental health as well our interaction with the environment for a healthier, happier life. This is a book should encourage clinicians to engage their patients more often and more practically with lifestyle medicine, and consumers to better engage with their clinicians, and to more effectively self-manage their own health in preventing and managing lifestyle-related illness for life.

  • Obesity

    Integrating Physiological, Pathophysiological and Clinical Perspectives
    • 1 Edición
    • Javier Gonzalez
    • Inglés
    Obesity: Integrating Physiological, Pathophysiological and Clinical Perspectives, a volume in Elsevier's Hot Topics in Physiology series, provides coverage across a wide range of physiological disciplines, covering obesity science at a sufficient level to be understood by physiologists who may not be an expert in all subdisciplines, and with an aim of unifying physiological perspectives on obesity. Divided into three sections, the book covers causes of obesity (e.g., regulation of energy balance), the consequences of obesity (e.g., metabolic, disease risk etc.), and strategies to prevent and/or manage obesity (e.g., bariatric surgery, pharmacotherapy, and lifestyle).This volume is published in association with the International Union of Physiological Sciences (IUPS). It will be of great interest for clinicians, dieticians, exercise physiologists, and molecular biologists.

  • Electrocardiography of Laboratory Animals

    • 3 Edición
    • Meg M. Sleeper + 1 más
    • Inglés
    Electrocardiography of Laboratory Animals, Third Edition, is an essential resource for biological and medical researchers, veterinarians, zoologists, and students. With the increasing global emphasis on the ethical care and use of laboratory animals in research, this comprehensive guide provides a standardized approach to performing and analyzing electrocardiograms (ECGs) across all species used in today’s research. The book provides the latest information on critical topics such as safety electrocardiography, toxicology, safety pharmacology, and telemetry, ensuring that readers are well-equipped with the knowledge required for accurate ECG interpretation in preclinical studies. The book is carefully organized into detailed chapters, beginning with the fundamental principles of electrocardiography and its application in drug safety evaluation. It covers the electrocardiography of a wide range of laboratory animals, including rodents, guinea pigs, rabbits, cats, dogs, and various non-human primates such as marmosets, cynomolgus monkeys, rhesus monkeys, baboons, and chimpanzees. Additionally, it reviews the ECG characteristics of minipigs, nanopigs, and micropigs. The text also includes chapters on telemetry and echocardiography in preclinical safety studies, as well as discussions on important parameters like PR (PQ), QRS, and QT intervals. The book concludes with chapters on cardiac assays, biomarkers, stem cells, and cardiovascular medical devices, providing a holistic view of cardiovascular research. This enhanced and expanded Electrocardiography of Laboratory Animals, Third Edition offers invaluable insights and practical guidance, making it an indispensable tool for those involved in the care and study of laboratory animals. Its comprehensive coverage and detailed explanations ensure that readers can confidently conduct and interpret ECGs, thereby advancing the field of preclinical safety evaluation and contributing to the ethical and effective use of animals in research.

  • Biofeedback and Pain Management

    A Clinical Guide
    • 1 Edición
    • Anu Kotay
    • Inglés
    Biofeedback and Pain Management: A Clinical Guide provides a detailed understanding of the psychophysiology of chronic pain, biofeedback treatments, the realities of living life with chronic pain limitations, and the role of pain in our lives and society. The book covers evidence on the effective uses of biofeedback interventions for pain management, including protocols, as well as case-based examples and strategies practitioners can use in real-life settings. Sections define biofeedback, including illustrations that depict how biofeedback is a useful part of any pain management treatment plan, cover procedures based on evidence and case examples, and present the social context of chronic pain.

  • The Complete Book of Coronary Artery Disease

    Anatomy, Physiology, Pathology, and Management
    • 1 Edición
    • Robert "Jay" Widmer
    • Inglés
    The Complete Book of Coronary Artery Disease: Anatomy, Physiology, Pathology, and Management covers various essential aspects related to the anatomy, embryology, anomalies, physiology, pathology, imaging, and disease management of the coronary system. The book highlights both invasive and non-invasive imaging techniques, with a focus on coronary CTA and CT-guided PCI. Intravascular imaging methods such as IVUS and OCT are elaborated on in assessing coronary health, along with a section on coronary anomalies and their incidence, diagnosis, and clinical implications. Meanwhile, information on coronary physiology explores non-pathological functions and adaptations to stressors.Coronary ischemia assessment using physiological parameters and unresolved questions regarding symptoms are also fundamental to this volume. Further, this book details coronary atherosclerosis, including pathological processes and treatment options. A non-atherosclerotic coronary anatomy section addresses pathologies impacting coronary arteries in other ways. For professionals seeking consolidated information on an oft-overlooked topic, they need look no further than this book.

  • Perianal Crohn’s Disease

    Diagnosis and Treatment
    • 1 Edición
    • Bolin Yang + 2 más
    • Inglés
    Perianal Crohn’s Disease: Diagnosis and Treatment includes the latest knowledge, concepts, first-hand theoretical views, and clinical experience of clinical frontline experts in the field of inflammatory bowel disease. The book systematically describes disease phenotypes, clinical features, examination methods, diagnoses, and treatments. It takes a scientific, practical, and systematic account of both common and rare conditions associated with Perianal Crohn’s Disease, offering informative content, clinical case information, cutting-edge viewpoints, and current, authoritative research findings. The book contains a depth of current clinical experience, including the use of photographs to support examples of conditions, methods, and techniques. In addition, it provides clear ideas and a wealth of clinical information for the clinical diagnosis and management of perianal Crohn's disease.

  • Biosimilars in Cancer

    • 1 Edición
    • Ranjita Shegokar + 1 más
    • Inglés
    Biosimilars in Cancer is a comprehensive resource addressing the role of biosimilars in treating various cancer types. This book offers a succinct yet thorough overview of current trends in oncology, covering 21 different cancers from liver to breast cancer. Each chapter provides detailed insights into the latest trends, fundamental facts, and practical and clinical data, making it an invaluable tool for academics and practitioners. By compiling this rich content into a single, accessible volume, the book empowers researchers and clinicians to enhance their understanding, and improve patient outcomes through the effective use of biosimilars in oncology. Targeted primarily at pharmaceutical researchers, biomedical scientists, and clinicians, Biosimilars in Cancer supports the growing oncology biosimilars market. It also provides critical insights for those involved in cancer diagnostics and clinical trials, helping them stay ahead in this rapidly progressing field.

  • Understanding Molecular Processes using Electrochemical Methods

    • 1 Edición
    • Ashis Kumar Satpati + 1 más
    • Inglés
    Understanding Molecular Processes using Electrochemical Methods offers a detailed compendium of techniques for molecular analysis. The book considers step and sweep techniques, scanning electrochemical microscopy, spectroelectrochemic... techniques, electrochemiluminesc... and scanning probe techniques while also exploring COSMOL multiphysics simulation, electroanalysis in biomedical and clinical applications, and future prospects for electrochemical techniques. Chapters focus on evaluating redox reactions, biological interactions, kinetics, quorum sensing, biofilm formation, surface modification and more molecular aspects. This volume offers a deep-dive into the fundamental principles behind the latest electrochemical techniques, equipping researchers with practical guidance for their own experiments.Users will find this to be an ideal reference for researchers working across a range of disciplines including molecular biology, bioanalytical chemistry, biomedical science, and translational medicine.

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