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Elsevier

Libros en Inmunología

  • Lateral Flow Assays for Rapid Point-of-care Testing

    Recent Advances, Emerging Trends, and Future Direction
    • 1 Edición
    • Seema Nara + 2 más
    • Inglés
    The emergence and re-emergence of new infectious diseases places emphasis on the need for greater investment in rapid healthcare diagnostic solutions. As a result, lateral flow immunoassay technology is quickly evolving with new inventions. Lateral Flow Assay for Rapid Point-of-Care Testing covers today’s most significant advancements, emerging trends, and future directions linked with this technology. The book begins with a review of the format, flow, and design of old-generation lateral flow assays and the challenges impeding performance before moving into innovation in materials for rapid test strips, advances in manipulating sample flow, and the latest developments in molecular imprinting and bioconjugation techniques. Subsequent sections cover various biorecognition elements and review signal amplification as well as quantification trends. Final chapters delve into recent applications for infectious diseases detection, monitoring antibiotic resistance, multiplex detection of analytes, as well as future directions leading to the next generation of healthcare. Academicians, researchers, industrialists, and device manufacturers linked to the development of rapid and affordable point-of-care immunodiagnostics will find value in this resource.

  • Inmunología

    • 10 Edición
    • David Male + 2 más
    • Español
    Nueva edición de uno de los textos de referencia en inmunología de nuestro portfolio en el que se abordan de forma equilibrada e integrada los conceptos pertenecientes a la inmunología básica y clínica. La estructura general de esta edición de Inmunología es la misma que la de la novena edición, Las secciones 1 y 2 describen el funcionamiento del sistema inmunitario. La sección 3 se ocupa de las respuestas inmunitarias contra los microorganismos patógenos (la función principal del sistema inmunitario), y las secciones 4 a 6 abordan aspectos de inmunología clínica, como las enfermedades autoinmunitarias, la inmunodeficiencia, los trasplantes, la inmunología tumoral y la hipersensibilidad. Todos los capítulos se han actualizado por completo e incluyen numerosos diagramas nuevos. Especial atención merecen los Caps. 17,18,20 y 22 por su profunda actualización en temas relativos a las nuevas vacunas de mRNA, inmunización pasiva, autoinmunidad, nuevos anticuerpos y nuevas terapias celulares y los nuevos descubrimientos a raíz de la epidemia de Covid. Las secciones de razonamiento crítico que siguen a cada capítulo requieren la comprensión del material presentado y de las implicaciones en un entorno de laboratorio o clínico, y sirven como base para el debate en el aula. Otro importante instrumento pedagógico son los resúmenes que recogen los puntos clave de cada capítulo, así como los numerosos esquemas, diagramas y figuras. La nueva edición ofrece contenido adicional online en español a través de la plataforma e-book+. Incluye apartados, tablas y figuras adicionales, así como una colección de 15 videos.

  • Endotoxin in Critical Illness

    • 1 Edición
    • John Kellum + 1 más
    • Inglés
    Endotoxin in Critical Illness intricately explores the theme of endotoxin and sepsis through the lenses of basic, clinical, and translational science. This work consolidates and synthesizes novel clinical insights and groundbreaking scientific discoveries into one comprehensive resource on endotoxic septic shock and sheds light on cutting-edge approaches in treatment. Beginning with a historical journey, the book traces the evolution of understanding from ancient concepts to modern molecular insights. It covers the physiological aspects of endotoxin sensitivity, tolerance, and human response variation. The crucial role of the gut microbiome in critical illness serves as a translational link between foundational science and clinical implications, and the complex language of bacterial communication is introduced, merging basic science with potential translational applications. In the clinical arena, chapters cover the critical role of endotoxin in septic shock, trauma, and its relevance in COVID-19, providing a translational bridge between laboratory findings and real-world clinical scenarios. The historical context of anti-endotoxin drug development is revisited, emphasizing the translational challenges faced in bridging basic science discoveries to clinical applications. The discussion on quantifying endotoxin concentration as well as the exploration of therapeutic rationale and clinical experiences with endotoxin removal therapy serve as a culmination of basic understanding translated into practical applications. The book concludes by contemplating the complexity of sepsis and acknowledging the challenges in achieving personalized medicine and underscoring the dynamic nature of the translational journey. In essence, this comprehensive exploration provides clinicians, researchers, and scientists with a holistic understanding of endotoxin and sepsis and potential advancements in patient care.

  • Myasthenia Gravis

    Disease, Diagnosis and Management
    • 1 Edición
    • Bhupendra G. Prajapati + 2 más
    • Inglés
    Myasthenia Gravis: Disease, Diagnosis and Management is a comprehensive resource that explores recent advancements in diagnosing and treating Myasthenia Gravis, a rare autoimmune disease affecting the neuromuscular junction. With contributions from global experts, this book addresses the increasing prevalence of Myasthenia Gravis, reflecting the latest in diagnostic techniques and novel therapies such as complement inhibitors and FcRn antagonists. It aims to support healthcare professionals in delivering optimal care through evidence-based insights and patient-centered approaches. The book is divided into several chapters, beginning with an overview of the pathogenesis and immunoregulatory defects in Myasthenia Gravis. Subsequent chapters cover diagnostic methods, non-immunosuppressiv... treatments, and biological therapies targeting the immune system. Key topics include the role of intravenous immunoglobulin (IVIg) and plasma exchange (PLEX) in severe exacerbations, thymectomy, molecular mechanisms, and the potential of hematopoietic stem cell transplants. The book also delves into precision medicine, AI applications, clinical trial considerations, and novel therapeutics like anti-FcRn antibodies. Management strategies for ocular Myasthenia Gravis, and a holistic view of living with the disease are also discussed. Myasthenia Gravis: Disease, Diagnosis and Management is invaluable for healthcare providers, physicians, immunologists, ophthalmologists, rheumatologists, physical therapists, pharmacists, and translators. It offers a modern guide to understanding and managing Myasthenia Gravis, integrating clinical expertise with the latest research to improve patient outcomes.

  • Advances in Management of Pediatric Brain Tumors

    • 1 Edición
    • Volumen 167
    • Inglés
    Advances in Management of Pediatric Brain Tumors, Volume 167 encapsulates the latest developments in the field for various types of pediatric brain tumors. By examining these survival gaps, the volume offers insights into strategies for improving outcomes and bridging the gap in care on a global scale. Chapters in this new release include Pediatric-type diffuse low grade gliomak, Pediatric-type diffuse high grade glioma/Diffuse Midline glioma, Ependymoma, Choroid plexus tumors, Embryonal tumors/medulloblasto... Craniopharyngioma and other sellar-region tumors, and much more.Other sections cover Germ cell tumors, Immunotherapy for pediatric brain tumors, Emerging interventional treatments in the management of pediatric brain tumors, and Management of pediatric brain tumors in low-middle income countries.

  • The Immunology of the Pig

    • 1 Edición
    • Ian R. Tizard
    • Inglés
    The Immunology of the Pig is a comprehensive and detailed exploration of the immune systems of domestic pigs, offering an invaluable resource for researchers, veterinarians, and students in the fields of immunology, veterinary medicine, and biomedical science. This text covers both the innate and adaptive immune systems of pigs, highlighting the unique features that make them an excellent model for human immune system studies. By examining the applied immunity of pigs, including available vaccines and immune-mediated diseases, this book addresses a critical need for understanding porcine immunology in both agricultural and biomedical contexts. The book is meticulously structured to cover a wide range of topics. It begins with the evolutionary origins and domestication of pigs, providing a historical context that enriches the understanding of their immune systems. Subsequent chapters explore key aspects of porcine immunology, including piglet ontogeny, reproduction, and lactation; innate immunity; hematology; cytokine functions; antigen processing cells; and lymphoid organs. Detailed discussions on the major histocompatibility complex, innate lymphoid cells, B and T cell systems, and immunity on body surfaces offer a thorough insight into the complex mechanisms at play. Additionally, the text addresses the microbiota's role, vaccination strategies, and immunity to various bacterial, viral, and parasitic diseases, rounding out a holistic view of porcine immune health.The Immunology of the Pig is an essential reference for anyone involved in veterinary science, immunology, or biomedical research. It provides a deep dive into the pig's immune system, presenting a wealth of information that is both scientifically rigorous and practically applicable. By understanding the parallels between porcine and human immune systems, researchers can leverage this knowledge to advance medical science, particularly in the areas of xenotransplantation and disease modeling. This book is a vital tool for advancing our understanding of immunology and improving health outcomes for both pigs and humans.

  • Encyclopedia of Immunobiology

    • 2 Edición
    • Paul Kaye
    • Inglés
    Encyclopedia of Immunobiology, Second Edition, Five Volume Set covers the full range of Immunology, presenting topics logically and making extensive use of "hot links" to refer the reader to related content. The new edition is not just an update of the original title; it vastly expands fields like immunotherapy, immunity to viral infection, vaccine development, inflammatory responses, and high throughput analyses. Containing 350 chapters written by world-leading experts, this edition integrates all concepts coherently and logically to paint a comprehensive picture of the evolving field of Immunology.The immune system, complex and multi-layered, has evolved to differentiate between "self" and foreign pathogens, providing protection against infections while dysregulation can cause diseases like autoimmunity, allergies, and inflammatory disorders. This understanding has led to numerous therapeutic interventions crucial for human health improvement.

  • Advances in Immunology

    • 1 Edición
    • Volumen 167
    • Inglés
    Advances in Immunology, Volume 167, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology. Chapters in this new release include Recent Advances in Antifungal Immunity, Neuroimmunology beyond the CNS: nerve-macrophage interactions in peripheral tissues, Regulatory T cell functions in peripheral tissues, Alarmins in mucosal tissues and how they regulate health and disease, Ontogeny and function of microglia and nerve-associated macrophages, and Modulation of humoral immunity by γδ T cells.

  • Mitochondrial Signaling and Regulation

    Immune Responses and Diseases
    • 1 Edición
    • Seyyed Shamsadin Athari + 1 más
    • Inglés
    Mitochondrial Signaling and Regulation: Immune Responses and Diseases delves into the latest research on molecular pathophysiology mechanisms and cell signaling pathways in the pathogenesis of diseases via mitochondrial regulation. This comprehensive study underscores the importance of mitochondria in cellular processes and their role in disease development. Early chapters discuss the crucial role, regulation, and crosstalk of mitochondria, highlighting their significance in maintaining cellular health. The exploration of mitochondria mutations and mitochondria-related diseases follows, providing a detailed understanding of the genetic aspects involved.Final chapters focus on mitochondria's involvement in immune responses and allegro-inflammation... presenting the intricate connections between mitochondrial function and the immune system. The book also explores the use of biotechnology in developing new treatments and targeted therapies against mitochondrial dysfunction. This resource sets the foundation for new classifications, prevention methods, therapies, and treatments of mitochondria-related diseases, making it invaluable for scientists and researchers dedicated to this field.

  • Cellular and Molecular Immunology

    • 11 Edición
    • Abul K. Abbas + 3 más
    • Inglés
    **Selected for 2026 Doody's Core Titles as an Essential Purchase in Immunology**Well-wri... readable, and superbly illustrated, Cellular and Molecular Immunology, Eleventh Edition, continues the tradition of excellence established through multiple editions of this bestselling text. Offering an unparalleled introduction to this complex field, it retains a practical, clinical focus while updating and revising all content to ensure clarity and comprehension, bringing readers fully up to date with new and emerging information in this challenging area. It's an ideal resource for medical, graduate, and undergraduate students, as well as a trusted reference for physicians and scientists.

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