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Elsevier

Libros en Inmunología Básica

  • Clinical Reproductive Immunology

    • 1 Edición
    • Karen E Racicot
    • Inglés
    Clinical Reproductive Immunology provides an up-to-date overview of clinical research in the field of reproductive immunology and pregnancy. With a strong focus on the use of clinical diagnostics to identify immune-related etiologies in pregnancy complications and/or failure, the book also addresses a significant informational gap by providing an overview of clinical data followed by a diagnostic algorithm at the end of each chapter. Every chapter addresses a significant information gap by providing a diagnostic algorithm that will serve to translate the findings from clinical research into a concise, stepwise guide developed with the clinical reproductive specialist in mind.This title builds nicely on the foundational Reproductive Immunology text and serves as a more concise diagnostic reference tool, addressing clinical utility and the significance of related research when developing background sections for manuscripts/literatu... reviews or for significant sections on grant proposals.

  • Advances in Cancer Research

    • 1 Edición
    • Volumen 172
    • Inglés
    Advances in Cancer Research, Volume 172 in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Memantine and its Analogs: Potential Applications in Cancer Therapy, The role of epigenetic modifications in mediating cancer health disparities, Tumor Associated Macrophages: Ontogeny, Plasticity, Spatial Ecosystems, and Therapeutic Targeting, Recognizing the significance of cancer-nerve crosstalk in advanced prostate cancer, and much more.

  • The Inflammatory Ecosystem and Inflammazones

    Mapping the Complex Terrain of Inflammatory Diseases
    • 1 Edición
    • Erwei Song + 1 más
    • Inglés
    The Inflammatory Ecosystem and Inflammazones offers a groundbreaking framework for understanding inflammation across multiple spatial and molecular levels. It introduces the concept of distinct inflammazones—local, regional, distal, and systemic—and explores how their interactions influence disease development, progression, and resolution. This holistic approach integrates cellular, molecular, microbiome, and systemic responses, addressing a critical gap in current knowledge and advancing diagnostics and therapies for diseases like autoimmunity and cancer. The book is organized into six sections, starting with foundational principles and progressing through mechanisms of local, regional, and systemic inflammazones. It covers key components such as cytokines, chemokines, immune cells, and the roles of non-immune cells like fibroblasts and epithelial cells. The final sections focus on systems-level insights, including inflammaging, metabolism, and multi-omics technologies, culminating in strategies for personalized medicine and clinical translation. Each chapter combines cutting-edge research with clinical relevance, making complex concepts accessible and actionable. The Inflammatory Ecosystem and Inflammazones is essential for researchers and clinicians seeking to understand the complex landscape of inflammation. It highlights disease heterogeneity, emerging therapeutic targets, and the importance of systems biology, providing the foundational knowledge to shape future inflammation research and treatment strategies.

  • Building Blocks of Neuroimmunometabolism

    From Molecular Pathways to Therapeutic Strategies
    • 1 Edición
    • Sachchida Nand Rai + 2 más
    • Inglés
    Building Blocks of Neuroimmunometabolis... From Molecular Pathways to Therapeutic Strategies offers an authoritative exploration of the intricate relationship between the immune system and neurodegenerative diseases. This essential resource addresses the critical gap in understanding how immune responses and metabolic processes jointly influence the onset and progression of conditions such as Alzheimer’s, Parkinson’s, and multiple sclerosis. The book provides a comprehensive examination of key molecular pathways and cellular interactions, emphasizing the role of immunometabolism in disease mechanisms.Beginning with an introduction to the concept of immunometabolism, the book explores the connections between the immune and nervous systems, setting the stage for understanding neurodegenerative diseases. It discusses pivotal topics such as the role of microglia and macrophages in neuroinflammation, the metabolic regulation of T cells, and the impact of oxidative stress and mitochondrial dysfunction. The gut-brain axis is examined for its influence on brain health, alongside innovative therapeutic strategies targeting immunometabolic pathways and lifestyle interventions.Buildi... Blocks of Neuroimmunometabolis... From Molecular Pathways to Therapeutic Strategies is invaluable for researchers, clinicians, and students seeking to understand the complex interactions driving neurodegeneration. The book offers cutting-edge insights into immunometabolism, highlighting its potential to revolutionize therapeutic strategies and improve patient outcomes in neurodegenerative disorders.

  • Viruses as Therapeutic Agents for Cancer

    • 1 Edición
    • Volumen 171
    • Inglés
    Viruses as Therapeutic Agents for Cancer, Volume 171 in the Advances in Cancer Research series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Coxsackievirus virotherapy, Oncolytic reovirus, Cancer immunotherapy with oncolytic myxoma virus, Zika Virus as an Oncolytic Therapy, Nonreplicative adenoviral vectors for cancer, VSV Oncolytic Virotherapy, AAV vectors for cancer gene therapy, Adenovirus cancer vaccines, Advancing Clinical Translation of Oncolytic Adenoviruses, and Immunotherapuetic Cancer Terminator Viruses.

  • The Immunology of Horses and Donkeys

    • 1 Edición
    • Ian R. Tizard
    • Inglés
    The Immunology of Horses and Donkeys offers a comprehensive overview of the immune systems of equids, bridging a critical gap by combining current research with foundational concepts and emphasizing both mechanisms and practical applications. The book covers immune development, disease resistance, vaccination, and immune disorders, supporting improved health management in horses and donkeys. Organized logically, it begins with the evolutionary history and domestication of equids and then explores immune ontogeny, innate and adaptive responses, and lymphoid tissue structure. Chapters detail the major histocompatibility complex, cytokine signaling, antigen-presenting cells, and mucosal immunity.Additional sections address the microbiota, vaccine strategies, and immune responses to bacterial, viral, and parasitic infections, providing a holistic view of equine immune health. Users will find content that advances understanding in immunology, biomedical research, and veterinary medicine, supporting the development of better diagnostics, vaccines, and therapies. The book's clear, thorough approach benefits both scientific discovery and clinical application, ultimately improving equine health and informing broader mammalian immunology studies.

  • Microglial Advances in Neurodegenerative Diseases

    • 1 Edición
    • Volumen 171
    • Inglés
    Microglial Advances in Neurodegenerative Diseases, Volume 170 in the Advances in Immunology series, presents current developments and comprehensive reviews focused on the role of microglia and neuroinflammation in neurological and psychiatric disorders. This volume brings together contributions from leading researchers, offering up-to-date insights into microglial biology in health and disease, as well as their involvement in major neurodegenerative conditions. Chapters in this new release explore Cross-talk between Tau and Neuro-glia Axis of Alzheimer’s Disease, Microglia in Health and Disease, Amyloid-beta (Aβ) and Neuroinflammation in Microglia, Chemokine Receptor CX3CR1 Interacts with Tau and Regulates Microglial Activity in Alzheimer’s Disease, and much more.Additional chapters explore Human-Induced Pluripotent Stem Cells in Psychiatric Disorders, GPCR-Mediated Internalization and Endosomal Sorting of the Tau–GPCR Complex in Microglia, iPSC-Derived Microglia: A Cellular Platform for Tau and Alzheimer’s Disease Immunotherapy, Advancements in Invasive and Non-Invasive Neuromodulation for Parkinson’s Disease, LRRK2-I1371V Disrupts Microglial Membrane Homeostasis and Enhances α-Synuclein Toxicity, Microglial Advances in Parkinson’s Disease, Microglial Advances in Alzheimer’s Disease, and more.

  • Microbiome in Head and Neck Cancer: Pathogenesis, Diagnosis and Therapeutic Implications

    Part B
    • 1 Edición
    • Volumen 170
    • Inglés
    Advances in Immunology, Volume 170 presents current developments and comprehensive reviews in immunology. This volume focuses on mechanisms of gasdermin activation and pyroptosis, providing insights into inflammatory cell death and immune signaling, and serving as a valuable reference for researchers in the field.

  • The Cytokines of the Immune System

    The Role of Cytokines in Disease Related to Immune Response
    • 2 Edición
    • Zlatko Dembic
    • Inglés
    Cytokines of the Immune System: The Role of Cytokines in Disease Related to Immune Response, Second Edition is a comprehensive and essential resource for graduate and postgraduate training of physicians, dentists, biomedical specialists, and those interested in scientific research in biology and biochemistry. The book provides an up-to-date, textbook-like description of immunology, focusing on the critical role of cytokines in immune responses. With advancements in cytokine research and signal transduction, this new and improved edition offers a deeper understanding of cytokine-receptor interactions, supported by novel figures based on crystal-structure conformations from the protein database.These insights are invaluable for inspiring new drug designs and therapeutic strategies. The book delivers a thorough overview of immunology, detailing the development and regulation of the immune system, with a special focus on cytokines. It presents an upgraded description of interleukins, immune-modulatory cytokines, and chemokines, exploring their structure, sources, functions, receptors, disease associations, and therapeutic potentials. This edition also introduces the latest information on innate lymphoid cells and their cytokines, as well as their adaptive immunity counterparts. A dedicated chapter on the cytokine storm provides critical insights into this phenomenon.

  • Systemic Lupus Erythematosus

    Basic, Applied and Clinical Aspects
    • 3 Edición
    • George C. Tsokos
    • Inglés
    Systemic Lupus Erythematosus: Basic, Applied and Clinical Aspects has been an essential resource for scientists and clinicians in this field since its original publication in 2015. The third edition of this work has been completely updated and expanded with the latest scientific and clinical developments in Systemic Lupus Erythematosus (SLE) to date. Contributors at the forefront of each topic come together to enhance content on epidemiology and diagnosis, pathogenesis, mechanisms of tissue damage, clinical aspects of the disease, antiphospholipid syndrome, and treatments. Also added is the latest information on new treatments, criteria, monogenic forms of lupus, insights on the role of microbiome, and advances in understanding disease pathogenesis. This must-have reference is an indispensable resource for specialists in the diagnosis and management of patients with SLE as well as early career or experienced investigators studying basic aspects of the disease. It is a tool for measurement of clinical activity for pharmaceutical development and basic research of the disease, and a key reference work for hospital libraries.