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Libros en Química

Green Approaches in Medicinal Chemistry for Sustainable Drug Design
Methods
2 Edición
Volumen 2
Bimal Banik
Inglés
Green Approaches in Medicinal Chemistry for Sustainable Drug Design: Methods, Second Edition reveals how medicinal chemistry can play a direct role in addressing this issue. After providing essential context on the growth of green chemistry in relation to drug discovery, the book identifies a range of practical techniques and useful insights, revealing how medicinal chemistry techniques can be used to improve efficiency, mitigate failure, and increase the environmental benignity of the entire drug discovery process. Drawing on the knowledge of a global experts, the book encourages the growth of green medicinal chemistry, and supports medicinal chemists, drug discovery researchers, pharmacologists, and more.This volume covers synthesis methods following green chemistry principles, contributing to sustainability by saving energy, using lesser toxic reagents/solvents/ca... and environmentally benign sources, including plants and agricultural materials.
The Chemistry of Hyperpolarized Magnetic Resonance Probes
1 Edición
Volumen 12
Eul Hyun Suh + 1 más
Inglés
The Chemistry of Hyperpolarized Magnetic Resonance Probes, Volume Seven focuses on the chemical aspects of hyperpolarized NMR/MRI technology, with synthesis and characterizations of labeled compounds discussed from a practical point-of-view. A brief overview of the various hyperpolarization techniques are given, with the optimization of hyperpolarization conditions and the determination of critical parameters such as polarization level and T1 relaxation values described. A practical guide on the in vivo applications of hyperpolarized compounds in small animals is also included.
Green Approaches in Medicinal Chemistry for Sustainable Drug Design
Applications
2 Edición
Volumen 1
Bimal Banik
Inglés
Sustainable and Green Approaches in Medicinal Chemistry: Applications, Second Edition reveals essential context on the growth of green chemistry in relation to drug discovery, identifying a broad range of practical techniques and useful insights and revealing how medicinal chemistry techniques can be used to improve efficiency, mitigate failure, and increase the environmental benignity of the entire drug discovery process. The book encourages the growth of green medicinal chemistry and supports medicinal chemists, drug discovery researchers, pharmacologists, and all those in related fields across both academia and industry in integrating these approaches into their own work.This volume includes the development of nanoparticles and nanocomposites, as well as the application of ultrasound and microwave-induced methods; studies solventless synthesis; defines the role of steroids; studies reactions in aqueous solution; identifies enzyme-mediated reactions; investigates ionic liquids and deep eutectic solvents; explores natural products; investigates solid supports; realizes the effects of salts; focuses on combinatorial chemistry; develops one-pot methods; analyzes multi-component reactions; investigates dipole moment values; and examines computer-assisted methods.
Photochemistry and Photophysics of Earth-Abundant Transition Metal Complexes
1 Edición
Volumen 83
Inglés
Photochemistry and Photophysics of Earth-Abundant Transition Metal Complexes, Volume 83 in the Advances in Inorganic Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Radioluminescence of Copper(I) Clusters, Photophysics and Photochemistry of Chromium(III) Complexes (Molecular Rubies), Chromic behaviors of luminescent copper(I) complexes, Long-lived photoluminescence in group 4 metal complexes enabled by ligand-to-metal charge transfer, Photoactive MOFs for CO2 Activation utilizing Earth Abundant Metals, and more.Other sections cover Earth Abundant Metal Complexes for Optoelectronic Applications, Photoactive metal to ligand charge transfer excited states in 3d6 and 3d8 complexes, Ligand-to-metal charge-transfer excited states in d0 transition-metal complexes: Investigations into the photochemistry and photophysics of emissive titanocenes, Ultrafast dynamics in photoactive copper complexes from optical and Xray methods, and Photophysical properties of Ni(II) complexes and some copper(I) and zinc(II) complexes.
Advances in Heterocyclic Chemistry
1 Edición
Volumen 144
Inglés
Advances in Heterocyclic Chemistry, Volume 144 highlights new advances in the field, with this volume presenting chapters on Metal free C-H functionalization of aromatic and non-aromatic heterocyclic systems, Divergent Total Synthesis of Indolizidine-, Quinolizidine-, and Decahydroquinoline-t... Poison-frog Alkaloids, A perspective on the synthetic potential of bio-based building blocks for heterocyclic chemistry, Recent advances in the synthesis of 3,3-disubstituted oxetanes, and Pyrrole-based chemosensors: Recent trends.
The Alkaloids
Chemistry and Biology
1 Edición
Volumen 91
Inglés
The Alkaloids: Chemistry and Biology, Volume 91, the newest release in a series that has covered the topic for more than 60 years, discusses key aspects of alkaloid chemistry, biology and pharmacology. Sections in this release include chapters on Recent Progress in the Chemistry of Naphthylisoquinoline Alkaloids.
Wave Optics in Infrared Spectroscopy
Theory, Simulation, and Modeling
1 Edición
Thomas G. Mayerhöfer
Inglés
Wave Optics in Infrared Spectroscopy starts where conventional books about infrared spectroscopy end. Whereas the latter are based on the Bouguer-Beer-Lambert law, the cornerstones of this book are wave optics and dispersion theory.This gap between both levels of theory is bridged to allow a seamless transition from one to the other. Based on these foundations, the reader is able to choose which level of theory is adequate for the particular problem at hand. Advanced topics like 2D correlation analysis, chemometrics and strong coupling are introduced and viewed from a wave optics perspective. Spectral mixing rules are also considered to better understand spectra of heterogeneous samples. Finally, optical anisotropy is examined to allow a better understanding of spectral features due to orientation and orientational averaging. This discussion is based on a 4 x 4 matrix formalism, which is used not only to simulate and analyze complex materials, but also to understand vibrational circular dichroism from a (semi-) classical point of view.Wave Optics in Infrared Spectroscopy is written as a tool to reunite the fragmented field of infrared spectroscopy. It will appeal to chemists, physicists, and chemical/optical engineers.
Advances in Organometallic Chemistry
1 Edición
Volumen 81
Inglés
Advances in Organometallic Chemistry, Volume 81 in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Specific chapters cover Recent Advances in the Catalytic Applications of NHC-Early Abundant Metals (Fe, Mn, Co) Complexes, A Guide to Non-Carbonyl, Non-Isocyano Organometallic Chemistry of Technetium-99 from Discovery to 2023, and Cyclopentadienyl, Amidinate (CPAM) Complexes of Groups 4 - 6 Transition Metals.
Comprehensive Chirality
2 Edición
Janine Cossy
Inglés
Comprehensive Chirality, Second Edition is the definitive ten-volume reference, offering a thorough exploration of chiral research and application. This extensively updated edition features 121 new chapters and 70 revised ones, focusing on the latest advancements in chiral research across synthesis, catalysis, analytical chemistry, and bioactive compound synthesis. Edited by a world-class editorial board, with contributions from leading experts, Comprehensive Chirality, Second Edition bridges theoretical principles with practical applications, making it an invaluable resource for advanced students, researchers, and professionals. Key highlights include:- Innovative Reactions and Methods: advanced diastereo- and enantioselective techniques for controlling stereogenic centers in complex natural products and pharmaceuticals.- Chiral Auxiliaries and Modern Reagents: transformative uses of chiral auxiliaries and cutting-edge reagents such as hypervalent iodide.- Catalytic Methodologies: comprehensive coverage of C-C bond formation, emphasizing transition metals, biocatalysis, and multicatalysis.- Asymmetric Photochemistry: light-induced asymmetric transformations.- Olefin Functionalization and Cycloaddition: asymmetric oxidation and reduction methods.- Biocatalysis and Enzyme Engineering: in-depth analysis of enzyme design and engineering as powerful synthesis catalysts.- Industrial Applications: practical insights into asymmetric synthesis for industrial applications, illustrated through recent case studies.- Spectroscopic Techniques: updated spectroscopic methods for separating and analyzing enantiomers.
Studies in Natural Products Chemistry
1 Edición
Volumen 81
Atta-Ur Rahman
Atta-Ur Rahman
Inglés
Studies in Natural Products Chemistry, Volume 81 covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting-edge accounts on fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects.With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry.

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