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Elsevier

Libros en Ciencias de la Vida

  • Dimensions In Health Research: Search For The Medicines Of Tomorrow

    • 1 Edición
    • Herbert Weissbach
    • Inglés
    Dimensions in Health Research: Search for the Medicines of Tomorrow is a collection of papers presented at the 1977 Symposium on Dimensions in Health Research: Search for the Medicines of Tomorrow, held in Basel, Switzerland, sponsored by the Roche Research Foundation for Scientific Exchange and Biomedical Collaboration. This symposium is organized in honor to Professor Alfred Pletscher, a known neurobiologist who led the discovery of drugs for the treatment of various central nervous disorders. This book is organized into three section encompassing 28 chapters. The first section covers the molecular biological aspects of gene expression; the biosynthesis of human interferon; the concept of DNA damage and repair; and the link between advances in molecular genetics and medicine. The second section discusses the pertinent advances in understanding the mechanism of immune system and its components. The third section surveys the trends in pharmacotherapy based on monoaminergic, adenosine triphosphate, gamma-amino butyric acid, amino acid, and peptide mechanisms. This book will prove useful to researchers in the fields of molecular biology, immunology, and neurobiology.

  • Plant Disease: An Advanced Treatise

    How Plants Defend Themselves
    • 1 Edición
    • James G. Horsfall
    • Inglés
    Plant Disease An Advanced Treatise, Volume V: How Plants Defend Themselves describes the active, passive, physical, chemical, mechanical, and physiological defense systems of plants against the pathogens. Divided into 23 chapters, this volume discusses theories, experimental approaches, and ways to help plant defend themselves. The opening chapters of this volume deal with certain general aspects of plant defense, such as the theories of “tolerance to disease” and “the time sequence of defense”, including a dynamic model of defense. A chapter discusses how plant populations defend themselves in natural ecosystem and the implications of disease management on agroecosystems. Considerable chapters examine the defense by the host by analogy with defense of a medieval castle, such as perimeter, internal, and chemical defenses. Discussions on the defenses triggered by the invading pathogen; recognition and compatibility phenomena; the concept of hypersensitivity; the role of phytoalexins in defense; and the metabolic detoxification done by plants to suffer less damage from toxins are provided. This volume also discusses the theory and mechanisms of hypovirulence and hyperparasitism. The concluding chapters summarize the effects of numerous nutrients on disease and the mechanisms involved. This volume is an invaluable source for plant pathologists, mycologists, advanced researches, and graduate students.

  • The Mycoplasmas V2

    Human and Animal Mycoplasmas
    • 1 Edición
    • J Tully
    • Inglés
    The Mycoplasmas, Volume II: Human and Animal Mycoplasmas is a volume of a comprehensive three-volume series encompassing various facets of mycoplasmology. This volume deals with host-parasite relationships of mycoplasmas in man and animals, with emphasis on recent developments in the study of classical mycoplasmal diseases of animals, such as cattle, sheep, goats, swine, and chickens. This volume shows the knowledge about mycoplasmal diseases of man, including those involving the respiratory and genitourinary tracts. Detailed information on the humoral and cellular immune responses to mycoplasmas,which are assuming an ever-increasing significance in the understandingof the pathogenesis of human and animal mycoplasmal diseases, is also given. This book ends with reviews on mycoplasmas as arthritogenic agents and the interaction of mycoplasmas with cell andorgan cultures. This book will serve as a standard reference work for mycoplasmologists, as well as for other interested microbiologists, cellular and molecular biologists, membrane biochemists, clinicians, veterinarians, plant pathologists, and entomologists.

  • Adenosine in the Nervous System

    • 1 Edición
    • Richard E. Stone
    • Inglés
    This volume in a series on neuroscience provides an overview of the last 20 years of research into the biochemistry, physiology,pharmacol... and clinical therapeutic potential of adenosine and its analogues in the nervous system. Among the topics covered are adenosine transport in nervous systemtissues, adenosine production and metabolism and the electropharmacology of adenosine.

  • Origins of Resistance to Toxic Agents

    • 1 Edición
    • M Sevag
    • Inglés
    Origins of Resistance to Toxic Agents contains the proceedings of the Symposium held in Washington, D.C. on March 25-27, 1954. Contributors theoretically explore the origins of drug resistance and related problems, based on the concept that the development of resistance to various toxic agents is associated with alterations and/or loss in enzyme proteins, and can explain the mutational and other processes. This text is organized into five sections encompassing 25 chapters and begins with an overview of the evolutionary aspects of resistance to antibacterial agents, herbicides, and insecticides. The book then discusses spontaneous and induced mutations to drug resistance in Escherichia coli, along with the mechanism of drug resistance in protozoa and bacteria, the physiological aspects of insect resistance to insecticides, and the enzymatic detoxication of DDT. The next chapters focus on the origins of tolerance and addiction to drugs and the problem of alcoholism; biochemical effects of narcotics and alcohol administration; tolerance and physical dependence to narcotics; and resistance and dependence in cancer cells. The book concludes by analyzing the significance of protein configuration to the specificity of biological interaction. This book is a valuable source of information for physicians, biochemists, pharmacologists, entomologists, plant physiologists, students of cancer, and those who are interested in the theory of the evolution of living matter.

  • Transport And Diffusion Across Cell Membranes

    • 1 Edición
    • Wilfred Stein
    • Inglés
    Transport and Diffusion across Cell Membranes is a comprehensive treatment of the transport and diffusion of molecules and ions across cell membranes. This book shows that the same kinetic equations (with appropriate modification) can describe all the specialized membrane transport systems: the pores, the carriers, and the two classes of pumps. The kinetic formalism is developed step by step and the features that make a system effective in carrying out its biological role are highlighted. This book is organized into six chapters and begins with an introduction to the structure and dynamics of cell membranes, followed by a discussion on how the membrane acts as a barrier to the transmembrane diffusion of molecules and ions. The following chapters focus on the role of the membrane's protein components in facilitating transmembrane diffusion of specific molecules and ions, measurements of diffusion through pores and the kinetics of diffusion, and the structure of such pores and their biological regulation. This book methodically introduces the reader to the carriers of cell membranes, the kinetics of facilitated diffusion, and cotransport systems. The primary active transport systems are considered, emphasizing the pumping of an ion (sodium, potassium, calcium, or proton) against its electrochemical gradient during the coupled progress of a chemical reaction while a conformational change of the pump enzyme takes place. This book is of interest to advanced undergraduate students, as well as to graduate students and researchers in biochemistry, physiology, pharmacology, and biophysics.

  • The Retina A Model for Cell Biology Studies Part_2

    • 1 Edición
    • Ruben Adler
    • Inglés
    The Retina: A Model for Cell Biology Studies, Part II, is the second of a two-part series that details developments in the study of retinal cell biology. The book begins with a review of the current evidence for the role of putative neurotransmitters at particular synapses in the retina. It then discusses pre- and postsynaptic regulatory mechanisms; the interactions of neurotransmitter-neu... systems; and cellular effects of putative neurotransmitters and neuromodulators. This is followed by an introduction to vision psychophysics, showing its application in studying the functioning of cells in the retina. The remaining chapters discuss how the retinal pigment epithelium cell might be used as a model for studying biological problems of current interest; extracellular matrix molecules; concepts and controversies regarding the biology of endothelial cells, the key elements in the phenomenon of intraocular neovascularization; the use of genetic mutations and genetic mosaics for the study of the retina; and the retina as a regenerating organ.

  • Milk Proteins V1

    Chemistry and Molecular Biology
    • 1 Edición
    • Hugh McKenzie
    • Inglés
    Milk Proteins: Chemistry and Molecular Biology, Volume I discusses the structure of evolution and biological function of milk proteins and enzymes. The milk proteins arise from a specific mammalian adaptation, and their study is important in its own right. However, the properties of milk proteins are such that their study has attained considerable importance in protein chemistry. In order to have a proper appreciation of the properties of milk proteins, this volume provides a general perspective and strategy for their study. This book is divided into three parts. Part A focuses on the historical survey of milk proteins, its comparative examination and characterization, and study of its immunological and allergenic reactions. Parts B and C discuss the basis of chemical and physical approaches most appropriate to the investigation of milk proteins. This publication is recommended to protein chemists and biochemists working in other areas. It will also serve as a good reference for advanced undergraduate and graduate students of milk protein chemistry.

  • Morphological Considerations

    • 1 Edición
    • Peter K.T. Pang
    • Inglés
    Vertebrate Endocrinology: Fundamentals and Biomedical Implications, Volume 1: Morphological Considerations provides information pertinent to vertebrate endocrine systems, which has significant contributions to basic biological and biomedical research. This book discusses the practical implications of the endocrinological studies. Organized into 15 chapters, this volume starts with an overview of the endocrine process in lower vertebrates, which has provided basic information about the understanding of mammalian and human systems. This text then discusses the pituitary gland, which is considered to be functionally and structurally the most complex organ of the endocrine system. Other chapters consider the function of the pineal organ as a sensory organ capable of perceiving light stimuli in poikilothermic vertebrates. This book discusses as well the caudal neurosecretory system in lampreys, hagfish, holocephalans, and dipnoans. The final chapter provides the comparative morphology of the classical vertebrate endocrine organs. Endocrinologists, biologists, graduate students, and researchers will find this book useful.

  • Development of Perception

    Psychobiological Perspectives
    • 1 Edición
    • Richard Aslin
    • Inglés
    Development of Perception: Psychobiological Perspectives, Volume 2, The Visual System, is the second of two-part series covering vision, audition, olfaction, taste, tactile sensitivity, and sensory-motor activity during ontogenesis. The focus is on approaches to perceptual development that incorporate a psychobiological perspective. The present volume brings together several topics of critical importance to the process of understanding the visual system. The book is organized into three parts. Part A addresses the theoretical and interpretive issues involved in designing and drawing conclusions from research on the development of the visual system. Part B on animal studies of visual development covers the neural and behavioral characteristics of the cat and monkey visual system during the early postnatal period. Part C examines visual development in human infants. Together, these three parts offer a comprehensive coverage of major issues in the structure and function of the developing mammalian visual system. Each chapter emphasizes the behavioral consequences of developing visual functions.

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