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Elsevier

Libros en Farmacología

  • Emerging Trends in Cancer Pharmacology

    From Molecular Targets to Personalized Medicine
    • 1 Edición
    • Tapan Behl + 4 más
    • Inglés
    Emerging Trends in Cancer Pharmacology: From Molecular Targets to Personalized Medicine gives readers a comprehensive and up-to-date resource on the latest developments and trends in the field of cancer pharmacology. It serves as a valuable reference for researchers, scientists, clinicians, and other professionals involved in cancer research, pharmacology, oncology, and personalized medicine. In recent years, there have been significant breakthroughs in understanding the molecular mechanisms of cancer and the development of targeted therapies. Additionally, personalized medicine has emerged as a promising approach to tailor treatments based on an individual's genetic profile, tumor characteristics, and other factors. These developments have the potential to revolutionize cancer treatment and improve patient outcomes. This book covers such developments.

  • Medicinal Plants

    Chemistry, Biology and Omics
    • 2 Edición
    • Da-Cheng Hao + 1 más
    • Inglés
    Medicinal Plants: Chemistry, Biology, and Omics, Second Edition is a reference to help researchers identify and master the patterns in the distribution of medicinal compounds on the phylogenetic tree to explore new drug resources and develop novel therapies against different diseases. The book provides a deeper understanding of how the interrelationship between phytometabolites, bioactivities and omics techniques facilitates sustainable conservation and application of phytomedicine resources. Now in 2nd edition, the contents have been updated to include topics as machine learning applications, geographic distribution of phytometabolites, comparative analysis of alkaloids, expanded coverage of selected taxa, and conditions like cardiovascular disease and cancer. The book is structured around chemotaxonomy. After an introduction and review of taxonomy, chemistry, biology and omics, the authors dive into a taxon-guided exploration of medicinal resources for Fritillaria, Chelidoniae, Dichocarpum, Aconitum, Cimicifugeae, Clematis, Potentilla, Rubus, Cannabis, and other taxa. All chapters follow a similar and consistent structure, offering detailed information on each of them. Researchers in phytopharmacology can acquire in-depth understanding of the interrelationships between chemistry, biology and omics, as well as the implications of the link between phylogeny, phytometabolites and bioactivities in medical biotechnology and sustainability. Clinicians can better understand the principles of mutual interactions between phytometabolites and drug efficacy.

  • Drug Metabolism in Diseases

    Leveraging Drug Metabolism and Disposition in Precision Medicine and Therapeutic Development
    • 2 Edición
    • Wen Xie
    • Inglés
    Drug Metabolism in Diseases: Leveraging Drug Metabolism and Disposition in Precision Medicine and Therapeutic Development, Second Edition provides essential knowledge for pharmaceutical scientists and biologists to understand the interplay between diseases and physiological conditions, impacting drug metabolism and its implications in personalized treatment. Expanded with six new chapters since the first edition, this updated book covers the latest scientific findings. Other important points include the book’s comprehensive reference on mutual effects between drug metabolism and diseases, implications in precision medicine, and therapeutic development. Pharmaceutical scientists, drug metabolism researchers, and research physicians will benefit from the expert insights provided.

  • Machine Learning in Drug Development: Part 2

    • 1 Edición
    • Volumen 65
    • Inglés
    Machine Learning in Drug Development: Part Two, Volume 65 in the Annual Reports on Medicinal Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Chapters in this volume explore Transforming Modern Drug Discovery with Machine Learning – Applications in Ligand-based Drug Design, Optimizing Multi-Modal Drug Design Through Computational Pocket Mapping and Data Integration, Harnessing AI for Nucleic Acid Drug Discovery: Small Molecule Targeting DNA and RNA, AI-aided Drug Development for Protein Degraders: Design, Lead Identification, and Optimization, and more.Additional section delve into Artificial Intelligence in the Development of Antiviral Drugs – Progress and Applications, Artificial Intelligence for Drug Target Identification, and Machine Learning in Proteomic Biomarker Discovery

  • Progress in Medicinal Chemistry

    • 1 Edición
    • Volumen 64
    • Inglés
    Progress in Medicinal Chemistry, Volume 64 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

  • Machine Learning in Drug Development: Part 1

    • 1 Edición
    • Volumen 64
    • Inglés
    Machine Learning in Drug Development: Part One, Volume 64 in the Annual Reports on Medicinal Chemistry series, highlights new advances in the field. Chapters in this release include Artificial Intelligence in Small Molecule and Nucleic Acid Research: A Review, AI-aided Drug Development for Protein Degraders: Design, Lead Identification, and Optimization, AI-aided Drug Development for Protein Degraders: Biology Validation, Disease-association, Drug Repurposing, Transforming Modern Drug Discovery with Machine Learning, Artificial Intelligence in the Development of Antiviral Drugs: Progress and Applications, Artificial Intelligence for Drug Target Identification, and Machine Learning in Proteomic Biomarker Discovery.

  • Handbook of Melatonin-Based Therapy and its Applications

    • 1 Edición
    • Alejandro Romero Martínez + 2 más
    • Inglés
    Handbook of Melatonin-Based Therapy and its Applications provides pharmaceutical researchers and health professionals with a comprehensive reference on the applications of melatonin in the therapeutic setting. Succinct, meticulously organized, and expertly written, this book addresses all essential aspects. It starts with an overview of safe use of melatonin, translational aspects, and its prospection. The next section of the book covers a variety of clinical applications, including dosage, pharmacokinetics and pharmacodynamic profiles, toxicity, and principles of action. The chapters in this section cover applications to both adults and pediatric patients suffering from conditions like skin cancers, GI issues, psychiatric, hepatic and ocular conditions.This is a comprehensive resource for pharmaceutical scientists and health professionals involved in developing therapies and applying them to patients. Researchers in the fields of medicine, biology, neuroscience, and pharmacology conducting studies related to melatonin-based will benefit from insights into the latest research findings, clinical trials, and therapeutic approaches.

  • Ketamine

    Fundamentals, Applications, Pharmacology, and Clinical Aspects
    • 1 Edición
    • Albert Dahan + 1 más
    • Inglés
    Pharmacology of Ketamine: Fundamentals, Applications, Delivery Systems and Clinical Aspects explores the multifaceted properties of ketamine for diverse applications, delving into dosing strategies, routes of administration, and their pharmacological implications. The book begins with an introduction that underscores the need to bridge research and practice. It then delves into the pharmacological intricacies of ketamine, dissecting mechanisms and dosing strategies and exploring the diverse routes of administration and their impact on ketamine's metabolites.The book then explores the PK and PD characteristics of ketamine, followed by a deep dive into clinical applications emphasizing anesthesia, psychiatric therapy, and emerging treatments. The final part of the book covers addiction, toxicity, and future research perspectives. It will serve as a comprehensive reference tailored to the needs of both researchers and clinicians involved in the administration and study of ketamine.

  • Comprehensive Toxicology

    • 4 Edición
    • Charlene McQueen
    • Inglés
    Comprehensive Toxicology, Fourth Edition, Fifteen Volume Set continues the legacy that began with the first edition in 1997, serving as an indispensable reference for toxicology researchers. This edition focuses on understanding the mechanisms by which chemicals affect biological systems and cause adverse health effects. Edited by a distinguished editorial board and featuring 400 in-depth contributions from experts around the globe, this comprehensive work spans fifteen volumes and nearly 9,000 pages, covering all major organ systems and general principles of toxicology. This extensively revised edition includes around 30 new chapters on modern testing strategies and novel in vitro models, such as organ-on-a-chip systems.It also explores computational approaches, new risk and safety assessment methods, harmonization, artificial intelligence, and the microbiome. As the most authoritative resource in toxicology, it continues to support researchers, faculty, and students in toxicology, as well as professionals in medical, veterinary, food, environmental, chemical, and pharmaceutical industries and international regulatory agencies.

  • Massachusetts General Hospital. Psicofarmacología y Neuroterapéutica

    • 2 Edición
    • Theodore A. Stern + 2 más
    • Español
    Información práctica y específica de uno de los principales hospitales y departamentos de psiquiatría del mundo. La segunda edición de Massachusetts General Hospital. Psicofarmacología y Neuroterapéutica es la guía ideal sobre los más actuales tratamientos psicofarmacológicos y somáticos para enfermedades psiquiátricas y neurológicas. Compuesta por capítulos extraídos principalmente de la tercera edición de Massachusetts General Hospital. Tratado de Psiquiatría Clínica, de Stern et al., la presente obra, exhaustivamente revisada, se centra en los tratamientos psicotrópicos actuales, la terapia electroconvulsiva y la neuroterapéutica, lo que la convierte en una herramienta de ágil consulta, ideal para psiquiatras, psicólogos, internistas y enfermeras.

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