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Elsevier

Libros en Microbiología y Virología

  • Sexually Transmitted Diseases

    Vaccines, Prevention, and Control
    • 1 Edición
    • Lawrence R. Stanberry + 1 más
    • Inglés
    There are 12 million new cases of sexually transmitted diseases every year.This growing world-wide problem has captured the concern of medical professionals, behavioural scientists, and public health officials.Sexually Transmitted Diseases: Vaccines, Prevention and Control provides a comprehensive assessment of the global epidemiology of sexually transmitted diseases plus current data on various strategies for controlling the epidemic, with particular focus on vaccines. The editors and authors represent the leading authorities in the field and provide international and multi-disciplinary expertise.This book is essential reading for all researchers and clinicians working in infectious diseases, virology, microbiology, immunology and vaccine development. This work will also be of key interest to medical students, physicians and workers in pharmaceutical and biotechnology companies and public and world health organisations.

  • Advances in Immunology

    • 1 Edición
    • Volumen 74
    • Inglés
    Advances in Immunology presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

  • Advances in Antiviral Drug Design

    • 1 Edición
    • Volumen 3
    • E. De Clercq
    • Inglés
    Volume 3 of Advances in Antiviral Drug Design is keeping up with the recent progress made in the field of antiviral drug research and highlights five specific directions that have opened new avenues for the treatment of virus infections. First, the use of lamivudine (3TC) for the treatment of HIV infections, and its more recent introduction for the treatment of hepatitis B virus (HBV) infections, has heralded the transition of D- to L-nucleosides in the antiviral nucleoside drug design, and it is likely that the future will provide more nucleosides of the L-configuration, such as (-)FFC (emtricitabine) and L-FMAU, as will be described by J.-C.G. Graciet and R.F. Shinazi. Second, the acyclic purine nucleoside phosphonates, i.e. PMEA (adefovir and PMPA (tenofovir), offer great potential as both anti-HIV and anti-HBV agents, and both compounds have been the subject of advanced clinical trials in their oral produrg form (adefovir dipivoxil and tenofovir disoproxyl), as mentioned by M.N. Arimilli, J.P. Dougherty, K.C. Cundy, and N. Bischofberger.Third, with the advent of nevirapine, delavirdine, and efavirenz, the NNRTIs have definitely come of age. Emivirine (MKC-442), a derivative of the original HEPT analog that was described in 1989 has now proceeded through pivotal clinical studies, and how this class of compounds evolved is presented in the account of H. Tanaka and his colleagues. Fourth, at the end of 1999, anticipating on the next winter influenza offensive, we should have at end two compounds that specifically inhibit influenza A and B virus infections: zanamivir (by the intranasal route) and oseltamivir (by the oral route). Both compounds have proved effective in the prophylaxis and treatment of influenza A and B virus infections and act through the same mechanism; that is by blocking the viral neuraminidase (or sialidase), a key enzyme that allows the virus to spread from one cell to another (within the respiratory mucosal tract). The design of these sialidase inhibitors will be presented by M. von Itzstein and J.C. Dyason.Fifth, the discovery (in 1996) of the chemokine receptors CXCR4 and CCR5 as essential coreceptors (in addition to the CD4 receptor) for HIV entry into the cells, has boosted an enormous interest in potential antagonists of these receptors. The bicyclams represent the first low-molecular-weight compounds targeted at CXCR4, the coreceptor used by the more pathogenic, T-lymphotropic, HIV strains, to enter the cells. They will be addressed by G.J. Bridger and R.T. Skerlj.The five topics covered in this third volume of Advances in Antiviral Drug Design are in the front line of the present endeavors towards the chemotherapy of virus infections. They pertain to the combat against three of the most important virus infections of current times: HIV, HBV, and influenza virus.

  • Women and Health

    • 1 Edición
    • Marlene B. Goldman + 1 más
    • Inglés
    Women and Health is a comprehensive reference which addresses health issues affecting women of all ages--adolescence through maturity. It goes far beyond other books on this topic which concentrate only on reproductive health, and has a truly international perspective. It covers key issues ranging from osteoporosis to breast cancer and other cancers, domestic violence, sexually transmitted diseases, occupational hazards, eating disorders, heart disease and other chronic illnesses, substance abuse, and societal and behavioral influences on health. Women and Health covers not only those conditions that are unique to or occur more frequently in women, but also those that present differently or are treated differently in women.

  • Biomedical Applications of Microprobe Analysis

    • 1 Edición
    • Peter Ingram + 3 más
    • Inglés
    Biomedical Applications of Microprobe Analysis is a combination reference/laboratory manual for the use of microprobe analysis in both clinical diagnostic and research settings. Also called microchemical microscopy, microprobe analysis uses high-energy bombardment of cells and tissue, in combination with high resolution EM or confocal microscopy to provide a profile of the ion, metal, and mineral concentrations present in a sample. This allows insight into the physiology and pathophysiology of a wide variety of cells and tissues.This book describes methods for obtaining detailed information about the identity and composition of particles too small to be seen with the naked eye and describes how this information can be useful in diagnostic and biomedical research.

  • Biofilms

    • 1 Edición
    • Volumen 310
    • John N. Abelson + 1 más
    • Inglés
    Volume 310 of Methods in Enzymology is the first volume devoted solely to biofilm research methods. It provides a contemporary source book for virtually any kind of experimental approach involving biofilms. It includes bioengineering, molecular, genetic, microscopic, chemical, continuous culture, and physical methods. This volume will serve as a starting point for future developments.The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.

  • Advances in Virus Research

    • 1 Edición
    • Volumen 54
    • Inglés

  • Advances in Virus Research

    • 1 Edición
    • Volumen 53
    • Inglés

  • Veterinary Virology

    • 3 Edición
    • Frederick A. Murphy + 3 más
    • Inglés
    Completely rewritten, this edition has expanded coverage of zoonotic viruses and the diseases they cause, and viruses and viral diseases of laboratory animals, poultry, fish, and wildlife. The concept of new emerging and reemerging viral diseases reflects the new perspective this concept has brought to veterinary and zoonotic virology and related fields.Part I presents fundamental principles of virology related to animal infection and disease. Part II details the properties and clinical features of the viruses that afflict animals and describes their treatment and control.

  • Advances in Parasitology

    • 1 Edición
    • Volumen 44
    • Inglés
    There are currently 3-5 million cases of leishmaniasis in the world and the prevalence is rising. The first chapter in this volume reviews the cell biology of the parasite and its transmission and survival. The second review addresses the apicomplexan protozoan parasites Theileria anulaga, T. parva and T. sergenti which globally cost agriculture over one billion US dollars annually. Current research in this area aims to produce effective, stable and cheap subunit viruses requiring only a single application and the authors predict that success will eventually be achieved with 'naked DNA' vaccines containing cytokine genes as immunopotentiators.T... next review is the first in over 30 years to discuss the larva of the class Monogenea.The authors cover morphology, behaviour and structure of many examples providing a detailed reference for researchers. The penultimate chapter discusses the distribution of Schistosoma bovis and considers the reported interactions occurring between parasites and snails. The final chapter reviews one of the most serious parasitic diseases in salmonid aquaculture - sealice. In 1998 the costs due to sealice damage in Scotland alone were estimated at 15-30 million pounds. Discussion of biology and control of these ectoparasites emphasizes the need to understand the basic biology of the parasite.This volume will be essential reading for parasitologists in many branches of the subject.

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