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Elsevier

Libros en Medicina

  • Advances in Melanoma, An Issue of Hematology/Oncology Clinics

    • 1 Edición
    • Volumen 23-3
    • David E. Fisher
    • Inglés
    The field of melanoma biology has experienced a remarkable surge in recent years, owing to progress which has ranged from the most basic laboratory/preclinic... discoveries to clinical developments that have begun to transform the management and prognosis for at least certain melanoma patients. Among the key areas that have contributed to this progress are studies relating to signaling and transcriptional pathways that regulate control over differentiation and survival of the melanocyte lineage. The identification of recurring activating mutations in specific signaling factors (B-RAF, N-Ras, c-KIT), amplification of other melanoma oncogenes (MITF, NEDD9), and the crucial recognition that certain of these genomic events occur within melanomas arising with specific clinical features (eg mucosal or acral origin) have led to clear recognition that melanoma is indeed “many different diseases.” While the various subclasses of melanoma may share common features, such as profound invasive and metastatic propensity, it is also likely that sharply focused therapeutic strategies may exploit the functionally critical molecular engines, which distinguish these subclasses. Certain strategies focus upon the immunogenicity and striking clinical opportunities afforded by immune modulation, while others focus more directly on tumor-specific targeting. This issue brings together some of the leaders who have contributed significant insights from basic melanoma biology to progress in the clinic.

  • Peptic Ulcer Disease, An Issue of Gastroenterology Clinics

    • 1 Edición
    • Volumen 38-2
    • Francis K.L. Chan
    • Inglés
    An ulcer is an open sore in the lining of the stomach or intestine. Peptic ulcers are eventually caused by acid and pepsin, a digestive stomach enzyme. These ulcers can occur in the stomach, where they are called gastric ulcers, or they can occur in the first portion of the intestine. These are called duodenal ulcers. Peptic ulcer is a term used to describe either or both of these two types of ulcers. H. pylori and certain drugs are the two major factors that cause ulcers. This issue provides a comprehensive overview of the causes, diagnosis, and treatments of peptic ulcers, including conditions like Zollinger -Ellison syndrome. Articles are devoted to NSAID ulcers and how to prevent them, stress ulcers, and antiplatelet therapy.

  • Skin Surgery and Minor Procedures, An Issue of Surgical Clinics

    • 1 Edición
    • Volumen 89-3
    • Frederick Radke
    • Inglés
    Melanoma; Pressure Ulcers; Wound Healing and Biology of the Skin; Local anesthetics-uses and toxicities; Approach to excision and closure of the skin; Unusual Skin Tumors; Dermatologic considerations for the General Surgeon; Suture choice and other skin closure methods; Benign and subcutaneous lesions; Common skin cancers and their precursors; Pilonidal cyst and benign perianal skin conditions

  • Cancer Emergencies, Part 1, An Issue of Emergency Medicine Clinics

    • 1 Edición
    • Volumen 27-2
    • Mohamud Daya + 1 más
    • Inglés
    First of a two-part issue dealing with Cancer Emergencies by Drs. Mohamud Daya and Charles Thomas. Topics with include: "Spinal Cord Compression," "Cerebral Edema," "Acute Renal Failure," "Electrolyte Disorders," and more!

  • Key Consultations in Hepatology, An Issue of Clinics in Liver Disease

    • 1 Edición
    • Volumen 13-2
    • Paul Martin
    • Inglés
    Often the hepatologist sees patients in consultation, and this issue focuses on how to deal with diagnosing, treating, and managing patients in the hospital on a consultation basis. The Guest Editor has assembled top experts to present articles on the asymptomatic outpatient with abnormal LFTs, surgery in the patient with liver disease, issues in long-term care of liver transplant recipients, management of autoimmune cholestatic liver disease, and current status of hepatitis vaccination and prophylaxis, to name a few.

  • Interventional Head and Neck Imaging, An Issue of Neuroimaging Clinics

    • 1 Edición
    • Volumen 19-2
    • Dheeraj Gandhi
    • Inglés
    Interventional Neuroradiology is a minimally invasive approach in the treatment of vascular diseases of the central nervous system. This exciting new issue of Neuroimaging Clinics, Guest Edited by Dheeraj Gandhi, includes such topics as: CT guided percutanous biopsies of the head and neck Dangerous collaterals in the head and neck Treatment of carotid-cavernous fistulae This issue is a must-have clinical resource.

  • Hypertensive Disease: Current Challenges, New Concepts, and Management, An Issue of Medical Clinics

    • 1 Edición
    • Volumen 93-3
    • Edward D. Frohlich
    • Inglés
    This issue of the Medical Clinics of North America brings the practicing clinician up to date on the current challenges, new concepts, and management of hypertensive disease. Topics covered include risks in hypertension; new biological concepts of target organ involvement in hypertension; hypertension and the metabolic syndrome; aging versus hypertension; hypertension, systolic blood pressure, and large arteries; oxidative stress, endothelial dysfunction, and hypertension; current thinking about hypertensive heart disease; diastolic dysfunction as a link between hypertension and heart failure; hypertension and cardiac failure in its various forms; hypertension and atherogenesis; the kidney, hypertension, and remaining challenges; current thinking about renovascular hypertension; obesity and hypertension; and barriers to adherence in hypertension management.

  • Embryology

    An Illustrated Colour Text
    • 2 Edición
    • Barry Mitchell + 1 más
    • Inglés
    EMBRYOLOGY provides a concise and highly illustrated text, which confines its descriptions to those that are relevant for modern undergraduate and postgraduate medical courses, and similar courses in other related disciplines. An appreciation of embryology is essential to understand topological relationships in gross anatomy and to explain many congenital anomalies. Each chapter is supplemented by clinical point ‘boxes’ and by key revision points.

  • Enhanced Endoscopic Imaging, An Issue of Gastrointestinal Endoscopy Clinics

    • 1 Edición
    • Volumen 19-2
    • Grace Elta + 1 más
    • Inglés
    Endoscopic imaging has become an important clinical tool for the diagnosis and treatment of gastrointestinal diseases and is poised to advance in a revolutionary fashion in the next few years. The articles in this issue are a result of an ASGE Imaging workshop held in early 2008. The goal of the workshop, and this issue, is to bring together clinical investigators and biophotonics engineers to help develop and clinically apply enhanced imaging technologies for the eventual benefit of patients. Articles in this issue are devoted to chromoendoscopy, autofluorescence endoscopy, reflectance spectroscopy, optical coherence tomography, laser confocal microscopy, and targeted endoscopic imaging to name a few.

  • Clinical Applications of MR Diffusion and Perfusion Imaging, An Issue of Magnetic Resonance Imaging Clinics

    • 1 Edición
    • Volumen 17-2
    • Scott B. Reeder + 1 más
    • Inglés
    Diffusion-weighted MR Imaging, Perfusion MR Imaging, and Diffusion Tensor Imaging provide information that is present in no other imaging modality. With Guest Editor Scott Reeder focusing on the body and Guest Editor Pratik Mukerjee exploring the neurological aspects of these three imaging modalities, this is a must-have resource for any radiologist involved in MR Imaging. It explores such subjects as: Diffusion weighted MR imaging in musculoskeletal radiology, Arterial Spin Labeled Perfusion Imaging, and Diffusion Tensor Imaging of Neurodegenerative Diseases.

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