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Role of Gut Microbiome in Neurodegenerative Disorders

  • 1 Edición - 29 de septiembre de 2025
  • Última edición
  • Editores: Mukesh Kumar Yadav, Balachandar Vellingiri
  • Idioma: Inglés

Role of Gut Microbiome in Neurodegenerative Disorders provides an overview of the gut microbiota and its interactions with the gut and the central nervous system. This book review… Leer más

Descripción

Role of Gut Microbiome in Neurodegenerative Disorders provides an overview of the gut microbiota and its interactions with the gut and the central nervous system. This book reviews the relevance of this axis to the pathogenesis of neurodegenerative diseases, such as Parkinson’s disease (PD), Alzheimer’s disease (AD), and Multiple sclerosis (MS). Various chapters discuss the effects of gut derived particles in various parts of brain and the targeting pathways leading to protein deposition in brain.

Puntos claves

  • Reviews the pathology and pathophysiology of gut derived neuropeptides in neurodegenerative disorders
  • Discusses mechanism of gut derivatives on immune system
  • Presents possible therapy mechanism using gut microbiome

De interès para

Clinical professionals, researchers and students in neurology, neuroscience, microbiology, and related subjects, like environmental medicine, complementary and alternative medicine

Índice

1. Overview of Neurodegenerative Disorders

2. Gut Microbiota and Neurological Diseases

3. Gut-Brain Axis

4. Gut-Brain Axis in Neurological Diseases

5. Difference in the constitution of Gut Microbiota during Neurodegenerative Disorders

6. Gut Metabolites in Neurodegenerative Diseases

7. Influence of Gut Microbiota on Cerebellum

8. Influence of Gut Microbiota on Hippocampus

9. Influence of Gut Microbiota on Axonal Cells of the brain

10. Mechanistic action of Gut Microbiota on Glial cells

11. Gut as a second brain- Largest producer of serotonin

12. Gradual Shift of gut microbial Population as a diagnostic marker for Neurodegenerative disorders

13. Gut metabolites – effective biomarker for Neurodegenerative disorder

14. Protocol – Isolation of Gut Microbiome from Faecal sample

15. Gut metabolites isolation from Blood

16. Metagenomics and sequence analysis

17. Computer aided detection method

18. Existing therapeutic options to alter gut composition in Neurodegenerative Disorders

19. Dietary and Gut microbiome

20. Ongoing clinical trials

21. Ethical hurdles for the treatment of a disease focusing Gut Microbiota

22. Futuristic therapies in pipeline for the betterment of Neurodegenerative Disorders

Detalles del producto

  • Edición: 1
  • Última edición
  • Publicado: 30 de septiembre de 2025
  • Idioma: Inglés

Sobre los editores

MY

Mukesh Kumar Yadav

Dr. Mukesh Kumar Yadav is working as Professor at the Department of Microbiology, Central University of Punjab, Bathinda, India. Prof. Yadav has more than 15 years of research experience in medical microbiology, particularly in microbial biofilms and host-microbial interactions. Prof. Yadav has published over 110 research articles, garnering more than 7,000 citations, and has authored five books with Elsevier. He has completed eight major research projects funded by the Indian Council of Medical Research (ICMR), the Department of Biotechnology (DBT), the Department of Science and Technology (DST), and the National Research Foundation (South Korea). Prof. Yadav's research area focuses on host-microbial interactions and microbial biofilms, including pathogenic and commensal bacteria in the gut. Prof. Yadav's lab is working on understanding microbial biofilms and infections caused by the biofilm mode of growth, as well as antimicrobial resistance (AMR), and identifying suitable strategies to combat AMR and drug resistance. Understanding Commensal Bacterial Interaction and Dysbiosis of Gut Microbiota during Various Metabolic Disorders.

Afiliaciones y experiencia
Professor, Department of Microbiology, Central University of Punjab, Bathinda, Punjab, India

BV

Balachandar Vellingiri

Dr. Balachandar Vellingiri currently is investigating various neurological diseases and developing human induced pluripotent stem cells (HiPSCs). Exploring the cutting-edge molecular, cellular, and translational neuroscience approaches, he aims to unravel disease mechanisms, identify therapeutic targets, and develop innovative interventions to slow or reverse neurological diseases. His expertise is on several techniques such as molecular cytogenetics, pathway analysis, and techniques in developing HiPSCs and Brain organoids, especially for neurological diseases.

Afiliaciones y experiencia
Associate Professor, Neurobiology (Ageing and Pediatric) Laboratory [NAP Lab], Department of Zoology, School of Basic Sciences, Central University of Punjab, Bathinda, Punjab, India

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