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Elsevier

Neurobiology of Aging

Exploring Cognitive Decline and Neurodegeneration

  • 1 Edición - 28 de noviembre de 2025
  • Última edición
  • Editor: Sachchida Nand Rai
  • Idioma: Inglés

Neurobiology of Aging: Exploring Cognitive Decline and Neurodegeneration is a comprehensive reference exploring the complexities of the aging brain. This book examines the intric… Leer más

Descripción

Neurobiology of Aging: Exploring Cognitive Decline and Neurodegeneration is a comprehensive reference exploring the complexities of the aging brain. This book examines the intricate processes driving cognitive decline and neurodegeneration. From the gradual loss of neurons and synapses to the formation of protein aggregates characteristic of Alzheimer's disease, each chapter reviews key aspects of brain aging. Chapters dissect the mechanisms driving neuronal loss, synaptic dysfunction, and protein misfolding, shedding light on the intricate interplay of oxidative stress, inflammation, and mitochondrial dysfunction. This book also navigates through strategies for healthy brain aging, from the impact of diet and exercise to the role of cognitive stimulation.

Puntos claves

  • Reviews the complex interplay of various molecular, cellular, and systemic processes that contribute to cognitive decline and neurodegeneration
  • Discusses genetic influences on aging and neurodegenerative diseases
  • Outlines various therapeutic approaches to age-related cognitive decline and neurodegenerative diseases

De interès para

Researchers and graduate students in neuroscience, psychology, aging, neurobiology, cognitive decline, and neurodegenerative diseases

Índice

Part 1: Mechanisms of Brain Aging

1. Introduction to the Neurobiology of Aging

2. Neuronal Loss and Synaptic Dysfunction

3. Protein Misfolding and Aggregation and its role in dementia with Lewy bodies

4. Oxidative Stress and Aging

5. Inflammation: Chronic Inflammation in Aging

Part 2: Factors Influencing Brain Aging

6. Mitochondrial Dysfunction and Aging

7. Neurotransmitter Systems in Aging

8. Genetic Influences on Aging and Neurodegenerative Diseases

9. Environmental and Lifestyle Factors in Brain Aging

10. The Role of Diet in Brain Health

Part 3: Interventions and Strategies for Healthy Brain Aging

11. Exercise and Cognitive Function in Aging

12. Unlocking Cognitive Vitality: The Interplay of Stimulation, Sleep, and Brain Aging

13. Exploring the Multifaceted Links Between Comorbidities and Cognitive Aging

14. Therapeutic Approaches to Age-Related Cognitive Decline and Neurodegenerative Diseases

15. Exploring Promising Pharmaceutical Candidates for Anti-Aging

Detalles del producto

  • Edición: 1
  • Última edición
  • Publicado: 8 de diciembre de 2025
  • Idioma: Inglés

Sobre el editor

SR

Sachchida Nand Rai

Dr. Sachchida Nand Rai is an Assistant Professor at University Centre for Research & Development (UCRD), Chandigarh University, Punjab, India. He obtained his MSc in Biochemistry from Purvanchal University, India, and his PhD in Biochemistry from Banaras Hindu University, India. Dr. Rai researches the anti-oxidative and anti-neuroinflammatory properties of phytochemicals for the treatment of neurodegenerative diseases. He is a lifetime member of the Indian Academy of Neuroscience.

Afiliaciones y experiencia
Assistant Professor

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