MRI of Brain Physiology

Novel Methods and Clinical Applications

1 Edición - 30 de junio de 2026
Última edición
Editores: Audrey P. Fan, Ahmed Khalil
Idioma: Inglés

MRI of Brain Physiology: Novel MRI Methods and Clinical Applications delves into the intricate world of brain physiology, focusing on the latest magnetic resonance imaging (MRI)… Leer más

Descripción

MRI of Brain Physiology: Novel MRI Methods and Clinical Applications delves into the intricate world of brain physiology, focusing on the latest magnetic resonance imaging (MRI) methods and their clinical applications. Designed for biomedical engineers, technologists, radiologists, neurologists, neurosurgeons, and clinical researchers, this resource bridges the gap between advanced imaging techniques and practical clinical use. It covers a wide spectrum of cerebral physiology, from microvascular and macrovascular dynamics to cerebrovascular reserve, neurovascular coupling, and cerebrospinal fluid pathways. Each of the core chapters has a tripartite structure: physiology (concepts of the physiological processes), imaging techniques, and clinical applications.

Readers will find detailed discussions on emerging MRI methods, including dynamic contrast, arterial spin labeling, and quantitative BOLD models. The book also addresses the functional impact of physiological changes on tissue microstructure and integrity, offering insights into multiparametric relaxation mapping and quantitative susceptibility mapping. Uniquely, this book gives a comparative approach to different brain physiological MRI methods, highlighting their strengths, limitations, and reliability.

Puntos claves

Organized around Key Cerebral Physiological Processes, with in-depth comparisons of different brain physiological MRI methods
Focuses on clinically relevant techniques, their specific applications, and actionable steps to facilitate their integration into clinical practice
Describes key brain physiological processes and their clinical significance in neurological conditions
Presents suitable functional or physiological MRI techniques that address specific clinical needs
Gives insights on the reliability, strengths, and limitations of state-of-the-art functional and physiological MRI methods

De interès para

Biomedical engineers, technologists, radiologists, neurologists, neurosurgeons, and clinical researchers

Índice

1. Overview of brain physiology and systems - anatomy (as related to neuroimaging)

2. Overview of brain physiology and systems - function

3. Microvascular brain physiology and perfusion imaging

4. Macrovascular brain physiology and hemodynamic timing

5. Cerebrovascular reserve and autoregulation

6. Neurovascular coupling and tissue metabolism

7. Cerebrospinal fluid pathways and flow imaging

8. Glymphatics and Blood Brain Barrier physiology

9. Functional/physiological coordination of hemodynamic systems

10. Functional impact on tissue microstructure and integrity

Detalles del producto

Edición: 1
Última edición
Publicado: 30 de junio de 2026
Idioma: Inglés

Sobre los editores

Audrey P. Fan

Audrey Fan develops new magnetic resonance imaging (MRI) and positron emission tomography methods to measure brain physiology and function. Dr. Fan is a Junior Fellow of the International Society of Magnetic Resonance in Medicine and currently co-leads the Imaging Core for the Alzheimer’s Disease Research Center at UC Davis Health. Her overall goal is to bridge engineers in her lab with clinicians and scientists to advance neuroimaging technology and promote brain vascular health across the entire lifespan.

Afiliaciones y experiencia

University of California, Davis, USA

Ahmed Khalil

Dr. Ahmed Khalil is a clinician-scientist in the Institute of Neuroradiology at the Charité – Universitätsmedizin Berlin. His research focuses on developing and clinically validating novel magnetic resonance imaging (MRI) techniques to assess brain hemodynamics, tissue oxygenation, and blood-brain barrier function. With a particular interest in the pathophysiology of stroke and cerebrovascular diseases, Dr. Khalil’s work bridges the gap between technical MRI methods and their clinical application to improve patient diagnosis and clinical decision-making. Beyond his primary research, he is an advocate for reproducible science, medical education, and science communication, and is an avid science writer and blogger. He holds postgraduate degrees in internal medicine and neuroscience from institutions across the UK, France, and Germany.