Animal Models of Disease Part F
- 1 Edición, Volumen 211 - 1 de diciembre de 2026
- Última edición
- Editores: Lorenzo Galluzzi, Jose Manuel Bravo-San Pedro, Fernando Aranda Vega
- Idioma: Inglés
Animal Models of Disease, Part F, Volume 212 in the Methods in Cell Biology series, presents significant advancements in understanding disease mechanisms through animal models… Leer más
Descripción
Descripción
Animal Models of Disease, Part F, Volume 212 in the Methods in Cell Biology series, presents significant advancements in understanding disease mechanisms through animal models. The book features chapters on timely topics such as characterizing tumor-infiltrating group 1 innate lymphoid cells in PyMT breast tumors and using zebrafish to unravel the molecular mechanisms of Alzheimer’s disease. The book also covers colitis mouse models and appropriate models for studying diabetes pathophysiology, demonstrating its comprehensive approach to current research.
Additional sections cover evaluating polyglutamine protein aggregation in transgenic Caenorhabditis elegans models of Huntington's disease and studying tumor responses to radioimmunotherapy in ovarian cancer models. It also highlights the antimicrobial regime for gut microbiota depletion in mice and the biodistribution of metallic nanoparticles for lymphoma studies. This book is an essential resource for researchers seeking to explore disease mechanisms and therapeutic approaches through animal models.
Additional sections cover evaluating polyglutamine protein aggregation in transgenic Caenorhabditis elegans models of Huntington's disease and studying tumor responses to radioimmunotherapy in ovarian cancer models. It also highlights the antimicrobial regime for gut microbiota depletion in mice and the biodistribution of metallic nanoparticles for lymphoma studies. This book is an essential resource for researchers seeking to explore disease mechanisms and therapeutic approaches through animal models.
Puntos claves
Puntos claves
- Provides the latest information on cancer research
- Offers outstanding and original reviews on a range of cancer research topics
- Serves as an indispensable reference for researchers and students alike
De interès para
De interès para
Molecular biologists, Biochemists, Cancer researchers, Immunologists, Neuroscientists
Índice
Índice
1. Comprehensive Methods for Pain Assessment in Rodents
Mario García Domínguez
2. Orthotopic pleural mesothelioma mouse model
Fernando Aranda, Pedro Berraondo and Miguel Sanmamed
3. Liver Metastasis Model Using Spleen Injection of MC38 Cells
Fernando Aranda and Pedro Berraondo
4. Orthotopic murine model of hepatocellularcarcinoma
Marta Ruiz, Leyre Silva and David Repáraz
5. Study of bone metastases in lung cancer: Intratibial model
Karmele Karmele
6. Live imaging of human colon cancer organoids/tumor associated fibroblasts and T cells for the study the effects of immunotherapies
Alvaro Teijeira, Mercedes Leal-Gómez, Inés Antomás, Maria Lucia Chiclana and Itziar Migueliz
7. Generation of 3D Organoids from DMBA/TPA-treated mice
Marta Montes and Niloufar Hosseini-Giv
8. The chorioallantoic membrane (CAM) assay as an in vivo model for B cell lymphoma
Laura Mondragon, Manon Durand, Barbara Chalhoub, Paula Carrasco, Arnau Julià Carbonell and Gaëtan Jego
9. An orthotopic model of pancreatic cancer for radiotherapy research
Juan Dubrot, Paolo Wong, Cristina Sainz, Myriam Fernandez-Sendin, Iratxe Ugarte and Ainhoa Andueza
10. Refine mouse models of liver carcinogenesis: versatility and clinical relevance
Maite G. Fernandez-Barrena
11. Orthotopic ovarian cancer model
Fernando Aranda
12. Preclinical Models to Induce and Study Acute Liver Failure
Marco Cordani
13. Preclinical Models to Induce and Study Liver Fibrosis and Cirrhosis
Marco Cordani
14. Preclinical Models to Establish and Study Fatty Liver Diseases
Marco Cordani
15. Experimental Methods to Study Liver Injury and Recovery in Preclinical Models
Marco Cordani
16. Ethical Considerations and Regulatory Translation in Developing and Application of Preclinical Models
Marco Cordani
17. Visualization of antigen display by follicular dendritic cells after vaccination
Ana Martinez Riaño
Mario García Domínguez
2. Orthotopic pleural mesothelioma mouse model
Fernando Aranda, Pedro Berraondo and Miguel Sanmamed
3. Liver Metastasis Model Using Spleen Injection of MC38 Cells
Fernando Aranda and Pedro Berraondo
4. Orthotopic murine model of hepatocellularcarcinoma
Marta Ruiz, Leyre Silva and David Repáraz
5. Study of bone metastases in lung cancer: Intratibial model
Karmele Karmele
6. Live imaging of human colon cancer organoids/tumor associated fibroblasts and T cells for the study the effects of immunotherapies
Alvaro Teijeira, Mercedes Leal-Gómez, Inés Antomás, Maria Lucia Chiclana and Itziar Migueliz
7. Generation of 3D Organoids from DMBA/TPA-treated mice
Marta Montes and Niloufar Hosseini-Giv
8. The chorioallantoic membrane (CAM) assay as an in vivo model for B cell lymphoma
Laura Mondragon, Manon Durand, Barbara Chalhoub, Paula Carrasco, Arnau Julià Carbonell and Gaëtan Jego
9. An orthotopic model of pancreatic cancer for radiotherapy research
Juan Dubrot, Paolo Wong, Cristina Sainz, Myriam Fernandez-Sendin, Iratxe Ugarte and Ainhoa Andueza
10. Refine mouse models of liver carcinogenesis: versatility and clinical relevance
Maite G. Fernandez-Barrena
11. Orthotopic ovarian cancer model
Fernando Aranda
12. Preclinical Models to Induce and Study Acute Liver Failure
Marco Cordani
13. Preclinical Models to Induce and Study Liver Fibrosis and Cirrhosis
Marco Cordani
14. Preclinical Models to Establish and Study Fatty Liver Diseases
Marco Cordani
15. Experimental Methods to Study Liver Injury and Recovery in Preclinical Models
Marco Cordani
16. Ethical Considerations and Regulatory Translation in Developing and Application of Preclinical Models
Marco Cordani
17. Visualization of antigen display by follicular dendritic cells after vaccination
Ana Martinez Riaño
Detalles del producto
Detalles del producto
- Edición: 1
- Última edición
- Volumen: 211
- Publicado: 15 de diciembre de 2026
- Idioma: Inglés
Sobre los editores
Sobre los editores
LG
Lorenzo Galluzzi
Lorenzo Galluzzi is Assistant Professor of Cell Biology in Radiation Oncology at the Department of Radiation Oncology of the Weill Cornell Medical College, Honorary Assistant Professor Adjunct with the Department of Dermatology of the Yale School of Medicine, Honorary Associate Professor with the Faculty of Medicine of the University of Paris, and Faculty Member with the Graduate School of Biomedical Sciences and Biotechnology of the University of Ferrara, the Graduate School of Pharmacological Sciences of the University of Padova, and the Graduate School of Network Oncology and Precision Medicine of the University of Rome “La Sapienza”. Moreover, he is Associate Director of the European Academy for Tumor Immunology and Founding Member of the European Research Institute for Integrated Cellular Pathology.
Galluzzi is best known for major experimental and conceptual contributions to the fields of cell death, autophagy, tumor metabolism and tumor immunology. He has published over 450 articles in international peer-reviewed journals and is the Editor-in-Chief of four journals:
OncoImmunology (which he co-founded in 2011), International Review of Cell and Molecular Biology, Methods in Cell biology, and Molecular and Cellular Oncology (which he co-founded in 2013). Additionally, he serves as Founding Editor for Microbial Cell and Cell Stress, and Associate Editor for Cell Death and Disease, Pharmacological Research and iScience.
Afiliaciones y experiencia
Assistant Professor of Cell Biology in Radiation Oncology, Department of Radiation Oncology, Weill Cornell Medical College, NY, USAJB
Jose Manuel Bravo-San Pedro
Jose Manuel Bravo-San Pedro is currently a researcher at the Department of Physiology of the Complutense University of Madrid thanks to a Ramon y Cajal contract grant. He got his Ph.D. in biochemistry, cellular biology and genetics from the University of Extremadura (Caceres, Spain) in 2011, and he did a post-doctoral stage in the laboratory of Prof. Guido Kroemer. His main research interests have always been linked to autophagy, addressing this cellular process associated with neurodegenerative diseases or cancer and recently obesity and specifically related to problems in the correct functioning of the cilium. He is co-inventor of two patents and co-author of 110 publications indexed in PubMed in prestigious international journals, with h-index 45 and 23768 cites (Dec 2022).
Afiliaciones y experiencia
Departamento de Fisiología, Facultad de Medicina, Universidad Complutense de Madrid, Madrid, SpainFA
Fernando Aranda Vega
Fernando Aranda holds a BSc in Biology (2006) and Biochemistry (2007) from the University of Navarra. Then, he specialized in different strategies of Cancer Immunotherapy with a MSc in Biomedical Research (2008), and a PhD Degree (2012) from the University of Navarra (Pamplona) – Cima University of Navarra. More than 12 years in translational research focus on antitumor immune responses and Cancer Immunotherapy. Author of 64 publications indexed in PubMed in prestigious international journals, with h-index 30 and 4,296 cites (October 2022). He completed the Program of Sara Borrell (ISCIII) -competitive Postdoctoral contract- in the Group of Immune Receptors of the Innate and Adaptive System (IDIBAPS), Barcelona (2016-2018). Co-author of 1 invention patent: Composition based on the fibronectin domain A for the treatment of melanoma - WO/2011/101332. In 2012, Fernando Aranda obtained a Scientific Award, "Profesor Durantez" II Edición, for the best scientific article in Tumor Immunology by Fundación LAIR. Recently, Fernando Aranda awarded a competitive Research Fellow contract “Miguel Servet tipo I” by Instituto de Salud Carlos III, to continue his independent researcher career (IP) in cancer immunotherapy issues. Specifically, he is involved in Translational Immunotherapy of Peritoneal Carcinomatosis. Currently, Fernando Aranda leads a research group in cooperation with Dr. Pedro Berraondo.
Afiliaciones y experiencia
Fernando Aranda Vega, CIMA Universidad de Navarra, Program of Immunology and Immunotherapy, Spain