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Elsevier

Advances in Antiviral Drug Design

  • 1 Edición, Volumen 5 - 30 de julio de 2007
  • Última edición
  • Editor: E. De Clercq
  • Idioma: Inglés

Regularly reviewing the "state-of-the-art" developments in the antiviral drug research field, this latest volume spans the conceptual design and chemical synthesis of new antiviral… Leer más

Descripción

Regularly reviewing the "state-of-the-art" developments in the antiviral drug research field, this latest volume spans the conceptual design and chemical synthesis of new antiviral compounds. It discusses their structure-activity relationship, mechanism and targets of action, pharmacological behavior, antiviral activity spectrum, and therapeutic potential for clinical use.

De interès para

Researchers, academics and postgraduates working in medical virology and infectious diseases, chemotherapy and drug discovery

Índice

Status presens of antiviral drugs and strategies, Part I: DNA viruses and retroviruses
Status presens of antiviral drugs and strategies, Part II: RNA viruses (except retroviruses)
Methylenecyclopropane analogues of nucleosides as anti-herpes agents
Synthesis and antiviral evaluation of broad spectrum orally active analogs of cidofovir and other acyclic nucleoside phosphonates
CCR5 antagonists for the treatment of HIV infection and AIDS
The medicinal chemistry of the DATA and DAPY series of HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs)

Detalles del producto

  • Edición: 1
  • Última edición
  • Volumen: 5
  • Publicado: 30 de julio de 2007
  • Idioma: Inglés

Sobre el editor

ED

E. De Clercq

Afiliaciones y experiencia
Rega Institute for Medical Research, Katholieke Universiteit Leuven, Belgium

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